Kevin L. Gunderson

TL;DR: An array-based whole-genome genotyping (WGG) assay using the BeadChip platform that effectively enables unlimited multiplexing and unconstrained single nucleotide polymorphism (SNP) selection and automation process increases assay robustness and throughput greatly while enabling laboratory information management system control of sample tracking.

TL;DR: In this article, the authors describe methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes, which relates generally to methods and devices for conducting analysis.

TL;DR: A new approach to comparative nucleic acid sequence analysis is described that uses the ligation of DNA targets to high-density arrays containing complete sets of covalently attached oligonucleotides of length eight and nine to demonstrate that complete n-mer arrays can correctly verify known sequences and determine the presence of sequence differences relative to a reference.

TL;DR: Ion current modulation through the protein nanopore MspA is used to observe translocation of helicase Hel308 on DNA with up to ∼40 pm sensitivity, applicable to any protein that translocates on DNA or RNA.

TL;DR: In this paper, a technique for sequencing nucleic acids in an automated or semi-automated manner is disclosed, in which sample arrays of a multitude of nucleic acid sites are processed in multiple cycles to add nucleotides to the material to be sequenced, detect the nucleotide added to sites, and to de-block the added nucleotide of blocking agents and tags used to identify the last added nucleotide. Quality control routines are run during sequencing to determine quality of samples, and quality of the data collected.