K
Khee Chee Soo
Researcher at National University of Singapore
Publications - 271
Citations - 12526
Khee Chee Soo is an academic researcher from National University of Singapore. The author has contributed to research in topics: Cancer & Hyperthermic intraperitoneal chemotherapy. The author has an hindex of 48, co-authored 265 publications receiving 10820 citations. Previous affiliations of Khee Chee Soo include The Royal Marsden NHS Foundation Trust & Singapore General Hospital.
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Journal ArticleDOI
Nanoparticles in photodynamic therapy.
TL;DR: This paper presents a meta-modelling study of the response of the immune system to chemotherapy and its applications in the context of central nervous system disorders.
Journal ArticleDOI
SIRveNIB: Selective Internal Radiation Therapy Versus Sorafenib in Asia-Pacific Patients With Hepatocellular Carcinoma
Pierce K. H. Chow,Mihir Gandhi,Say Beng Tan,Maung Win Khin,Ariunaa Khasbazar,Janus P. Ong,Su Pin Choo,Peng Chung Cheow,Chanisa Chotipanich,Kieron Lim,Laurentius A. Lesmana,Tjakra Manuaba,Boon Koon Yoong,Aloysius Raj,Chiong Soon Law,Ian Homer Y. Cua,Rolley Rey Lobo,Catherine Teh,Yun Hwan Kim,Yun Won Jong,Ho-Seong Han,Si Hyun Bae,Hyun-Ki Yoon,Rheun Chuan Lee,Chien Fu Hung,Cheng Yuan Peng,Po-Chin Liang,Adam Bartlett,Kenneth Y.Y. Kok,Choon Hua Thng,Albert S. C. Low,Anthony S. W. Goh,Kiang Hiong Tay,Richard Hoau Gong Lo,Brian K. P. Goh,David Chee Eng Ng,Ganesh Lekurwale,Wei Ming Liew,Val Gebski,Kenneth Seck Wai Mak,Khee Chee Soo +40 more
TL;DR: In patients with locally advanced HCC, OS did not differ significantly between RE and sorafenib, and the improved toxicity profile of RE may inform treatment choice in selected patients.
Journal ArticleDOI
Oncogenic Pathway Combinations Predict Clinical Prognosis in Gastric Cancer
Chia Huey Ooi,Tatiana Ivanova,Jeanie Wu,Minghui Lee,Iain Beehuat Tan,Jiong Tao,Lindsay C. Ward,Jun Hao Koo,Veena Gopalakrishnan,Yansong Zhu,Lai Ling Cheng,Julian Lee,Sun Young Rha,Hyun Cheol Chung,Kumaresan Ganesan,Jimmy Bok Yan So,Khee Chee Soo,Dennis T. H. Lim,Weng Hoong Chan,Wai-Keong Wong,David D.L. Bowtell,Khay Guan Yeoh,Heike Grabsch,Alex Boussioutas,Alex Boussioutas,Patrick Tan +25 more
TL;DR: Using gene expression signatures, this paper identified major oncogenic pathways in gastric cancer (GC) with significant relationships to patient survival, and devised an in-silico strategy to map patterns of pathway activation in 301 primary gastric cancers, the second highest cause of global cancer mortality.
Journal ArticleDOI
Titania coated upconversion nanoparticles for near-infrared light triggered photodynamic therapy.
Sasidharan Swarnalatha Lucky,Niagara Muhammad Idris,Zhengquan Li,Kai Huang,Khee Chee Soo,Yong Zhang +5 more
TL;DR: This work presents a method to fabricate uniform core-shell structured nanoconstruct with a thin layer of photocatalyst or PS-titanium dioxide (TiO2) stably coated on individual UCN core, allowing controllable and highly reproducible PS loading, ensuring repeatable PDT results.
Journal ArticleDOI
Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: Its role in tumor progression and apoptosis
Hung Huynh,Thi Thanh Tuyen Nguyen,Kah-Hoe Kah-Pierce Chow,Puay Hoon Tan,Khee Chee Soo,Evelyne Tran +5 more
TL;DR: The results demonstrate that MEK-MAPK plays an important role in the growth and survival of liver cancer cells and suggest that blocking MEK1/2 activity may represent an alternative approach for the treatment of Liver cancer.