K
Khushwant S. Bhullar
Researcher at University of Alberta
Publications - 44
Citations - 1870
Khushwant S. Bhullar is an academic researcher from University of Alberta. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 12, co-authored 30 publications receiving 1264 citations. Previous affiliations of Khushwant S. Bhullar include Dalhousie University.
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Kinase-targeted cancer therapies: progress, challenges and future directions
Khushwant S. Bhullar,Naiara Orrego Lagarón,Eileen M. McGowan,Indu Parmar,Amitabh Jha,Basil P. Hubbard,H.P. Vasantha Rupasinghe +6 more
TL;DR: The human genome encodes 538 protein kinases that transfer a γ-phosphate group from ATP to serine, threonine, or tyrosine residues, which are the second most targeted group of drug targets, after the G-protein-coupled receptors.
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Polyphenols: multipotent therapeutic agents in neurodegenerative diseases.
TL;DR: Although current polyphenol researches have limited impact on clinical practice, they have strong evidence and testable hypothesis to contribute clinical advances and drug discovery towards age-related neurological disorders.
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Lifespan and healthspan extension by resveratrol.
TL;DR: The origins and molecular targets of resveratrol are discussed and an overview of its effects on the lifespan of simple model organisms and mammals are provided and potential approaches for realizing the possibility of human lifespan extension are examined.
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Curcumin and its carbocyclic analogs: structure-activity in relation to antioxidant and selected biological properties.
TL;DR: Curcumin and 15 novel analogs were investigated for their antioxidant and selected biological activities and Cytotoxicity studies using normal human lung cells revealed that the novel curcumin as well as its carbocyclic analogs are not toxic.
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Antihypertensive effect of caffeic acid and its analogs through dual renin-angiotensin-aldosterone system inhibition.
TL;DR: Caffeic acid along with its nineteen novel derivatives, chlorogenic acid, quercetin and captopril were investigated for the inhibition of renin and angiotensin converting enzyme (ACE) activities and production of aldosterone and toxicity analysis confirmed the non-toxic manifestations of caffeic acid and its derivatives.