K
Kimberly K. Jefferson
Researcher at Virginia Commonwealth University
Publications - 84
Citations - 7332
Kimberly K. Jefferson is an academic researcher from Virginia Commonwealth University. The author has contributed to research in topics: Bacterial vaginosis & Gardnerella vaginalis. The author has an hindex of 41, co-authored 82 publications receiving 6067 citations. Previous affiliations of Kimberly K. Jefferson include National Institutes of Health & University of Virginia.
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Journal ArticleDOI
What drives bacteria to produce a biofilm
TL;DR: The currently available wealth of data pertaining to the molecular genetics of biofilm formation in commonly studied, clinically relevant, single-species biofilms will be discussed in an effort to decipher the motivation behind the transition from planktonic to sessile growth in the human body.
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The vaginal microbiome and preterm birth
Jennifer M. Fettweis,Myrna G. Serrano,J. Paul Brooks,David J. Edwards,Philippe H. Girerd,Hardik I. Parikh,Bernice Huang,Tom Arodz,Laahirie Edupuganti,Abigail L. Glascock,Jie Xu,Nicole R. Jimenez,Stephany C. Vivadelli,Stephen S. Fong,Nihar U. Sheth,Sophonie Jean,Vladimir Lee,Yahya Bokhari,Ana M. Lara,Shreni D. Mistry,Robert A. Duckworth,Steven P. Bradley,Vishal N. Koparde,X. Valentine Orenda,Sarah Milton,Sarah K. Rozycki,Andrey V. Matveyev,Michelle L. Wright,Michelle L. Wright,Snehalata Huzurbazar,Eugenie M. Jackson,Ekaterina Smirnova,Ekaterina Smirnova,Jonas Korlach,Yu-Chih Tsai,Molly R. Dickinson,Jamie L. Brooks,Jennifer I. Drake,Donald O. Chaffin,Amber L. Sexton,Michael G. Gravett,Craig E. Rubens,N. Romesh Wijesooriya,Karen D. Hendricks-Muñoz,Kimberly K. Jefferson,Jerome F. Strauss,Gregory A. Buck +46 more
TL;DR: A community resource that includes ‘omics’ data from approximately 12,000 samples as part of the integrative Human Microbiome Project is reported, identifying harbingers of preterm birth in this cohort of women predominantly of African ancestry.
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The truth about metagenomics: quantifying and counteracting bias in 16S rRNA studies
J. Paul Brooks,David J. Edwards,Michael D. Harwich,Maria C. Rivera,Jennifer M. Fettweis,Myrna G. Serrano,Robert Reris,Nihar U. Sheth,Bernice Huang,Philippe H. Girerd,Jerome F. Strauss,Kimberly K. Jefferson,Gregory A. Buck +12 more
TL;DR: An experimental protocol using mock communities for quantifying and characterizing bias introduced in the sample processing pipeline and developed models to predict the “true” composition of environmental samples based on the observed proportions, which were applied to clinical vaginal samples from a single subject during four visits.
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Differences in vaginal microbiome in African American women versus women of European ancestry
Jennifer M. Fettweis,J. Paul Brooks,Myrna G. Serrano,Nihar U. Sheth,Philippe H. Girerd,David J. Edwards,Jerome F. Strauss,Kimberly K. Jefferson,Gregory A. Buck +8 more
TL;DR: Findings support and extend previous findings that there are significant differences in the vaginal microbiome related to ethnicity and demonstrate that these differences are pronounced even in healthy women.
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Use of Confocal Microscopy To Analyze the Rate of Vancomycin Penetration through Staphylococcus aureus Biofilms
TL;DR: It is found that while vancomycin bound to free-floating bacteria in water within 5 min, it took more than 1 h to bind to cells within the deepest layers of a biofilm, indicating that the antibiotic is transported through the depth of the biofilm but that the rate is significantly reduced with respect to its transport through flowing water.