K
Kimberly T. LeBlanc
Researcher at University of Massachusetts Medical School
Publications - 4
Citations - 625
Kimberly T. LeBlanc is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Mesenchymal stem cell & GATA transcription factor. The author has an hindex of 4, co-authored 4 publications receiving 571 citations.
Papers
More filters
Journal ArticleDOI
miRNA Signatures Associate with Pathogenesis and Progression of Osteosarcoma
Kevin B. Jones,Zaidoun Salah,Sara Del Mare,Marco Galasso,Eugenio Gaudio,Gerard J. Nuovo,Francesca Lovat,Kimberly T. LeBlanc,Jeff Palatini,R. Lor Randall,Stefano Volinia,Gary S. Stein,Carlo M. Croce,Jane B. Lian,Rami I. Aqeilan +14 more
TL;DR: A miRNA signature associated with pathogenesis of osteosarcoma as well as critical pre-treatment biomarkers of metastasis and responsiveness to therapy is established.
Journal ArticleDOI
Fibronectin binding protein BBK32 of the Lyme disease spirochete promotes bacterial attachment to glycosaminoglycans.
TL;DR: It is shown that, when BBK32 was produced from a shuttle vector in an otherwise nonadherent high-passage B. burgdorferi strain, the protein localized on the bacterial surface and conferred attachment to fibronectin and to mammalian cell monolayers.
Journal ArticleDOI
Control of Mesenchymal Lineage Progression by MicroRNAs Targeting Skeletal Gene Regulators Trps1 and Runx2
Ying Zhang,Ronglin Xie,Jonathan A. R. Gordon,Kimberly T. LeBlanc,Janet L. Stein,Jane B. Lian,Andre J. Van Wijnen,Gary S. Stein +7 more
TL;DR: A program of multiple miRNAs controls mesenchymal lineage progression by selectively blocking differentiation of osteoblasts and chondrocytes to control skeletal development.
Journal ArticleDOI
Runx1 Activities in Superficial Zone Chondrocytes, Osteoarthritic Chondrocyte Clones and Response to Mechanical Loading
Kimberly T. LeBlanc,Marie Walcott,Tripti Gaur,Shannon L. O'Connell,Kirti Basil,Christina P. Tadiri,April Mason-Savas,Jason A. Silva,Andre J. Van Wijnen,Janet L. Stein,Gary S. Stein,David C. Ayers,Jane B. Lian,Paul J. Fanning +13 more
TL;DR: It is proposed that Runx1 co‐expression with Vcam1 and lubricin in murine cell clusters and human ‘clones’ of OA cartilage, participate in a cooperative mechanism for a compensatory anabolic function.