K
Kirsten H. W. J. ten Tusscher
Researcher at Utrecht University
Publications - 34
Citations - 1412
Kirsten H. W. J. ten Tusscher is an academic researcher from Utrecht University. The author has contributed to research in topics: Auxin & Gene regulatory network. The author has an hindex of 14, co-authored 34 publications receiving 1155 citations. Previous affiliations of Kirsten H. W. J. ten Tusscher include Simula Research Laboratory & University of Ljubljana.
Papers
More filters
Journal ArticleDOI
PLETHORA gradient formation mechanism separates auxin responses
Ari Pekka Mähönen,Ari Pekka Mähönen,Kirsten H. W. J. ten Tusscher,Riccardo Siligato,Ondrej Smetana,Sara Diaz-Trivino,Sara Diaz-Trivino,Jarkko Salojärvi,Guy Wachsman,Kalika Prasad,Renze Heidstra,Renze Heidstra,Ben Scheres,Ben Scheres +13 more
TL;DR: It is demonstrated how this specific regulatory design in which auxin cooperates with PLTs through different mechanisms and on different timescales enables both the fast tropic environmental responses and stable zonation dynamics necessary for coordinated cell differentiation.
Journal ArticleDOI
Organization of Ventricular Fibrillation in the Human Heart
TL;DR: This work uses a detailed model of the human ventricles, including a detailed description of cell electrophysiology, ventricular anatomy, and fiber direction anisotropy, to study the organization of human VF and finds that human Vf is driven by only approximately 10 reentrant sources and thus is much more organized than VF in animal hearts of comparable size.
Journal ArticleDOI
Polar auxin transport: models and mechanisms.
TL;DR: It is suggested that current models cannot explain the bidirectional fountain-type patterns found in plant meristems in a fully self-organised manner, and future research directions are discussed to address the gaps in the understanding of auxin transport mechanisms.
Journal ArticleDOI
Influence of diffuse fibrosis on wave propagation in human ventricular tissue
TL;DR: It is shown that diffuse fibrosis slows down wave propagation and increases tissue vulnerability to wave break and spiral wave formation, and suggests that mechanisms different from restitution-induced spiral break-up might be more likely to account for the onset of fibrillation in the presence of large amounts of diffuse fibrotic tissue.
Journal ArticleDOI
Comparison of electrophysiological models for human ventricular cells and tissues.
TL;DR: This paper discusses the application of a subset of these models-the redPB and the TNNP model-to study simulated spiral wave dynamics in 2D tissue sheets and in the human ventricles and discusses the suitability of the different models for particular research questions and their limitations.