K
Kiyoshi Asai
Researcher at University of Tokyo
Publications - 200
Citations - 11475
Kiyoshi Asai is an academic researcher from University of Tokyo. The author has contributed to research in topics: Gene & Nucleic acid secondary structure. The author has an hindex of 46, co-authored 192 publications receiving 10456 citations. Previous affiliations of Kiyoshi Asai include National Institute of Advanced Industrial Science and Technology & Nara Institute of Science and Technology.
Papers
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Journal ArticleDOI
Capturing alternative secondary structures of RNA by decomposition of base-pairing probabilities.
TL;DR: A new computational method to detect essential alternative secondary structures from RNA sequences by decomposing the base-pairing probability matrix is proposed, and it is shown thatAlternative secondary structures are captured by decompose base-paring probabilities over Hamming distance.
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Shape-based alignment of genomic landscapes in multi-scale resolution
TL;DR: By applying this method to over 20 genomic landscapes in human and mouse, it is found that DNA replication timing and the density of Alu insertions are highly correlated genome-wide in both species, even though the Alu elements have amplified independently in the two genomes.
Journal ArticleDOI
Evolutionary design of multiple genes encoding the same protein.
Goro Terai,Goro Terai,Satoshi Kamegai,Satoshi Kamegai,Akito Taneda,Kiyoshi Asai,Kiyoshi Asai +6 more
TL;DR: This work proposes a method for designing multiple protein‐coding sequences (CDSs) that are unlikely to induce homologous recombination, while encoding the same protein, and provides insight into the trade‐off between nucleotide differences among gene copies and codon usage frequencies.
Patent
Koji mold-origin phospholipase a2
Katsuhiko Kitamoto,Manabu Arioka,Shotaro Yamaguchi,Masayuki Machida,Keietsu Abe,Katsuya Gomi,Kiyoshi Asai,Motoaki Sano,Taishin Kin,Hideki Nagasaki,Akira Hosoyama,Osamu Akita,Naotake Ogasawara,Satoru Kuhara +13 more
TL;DR: In this article, the koji mold-origin phospholipase A 2 and a DNA encoding were used to provide koji-mold-origin PAS and DNA encoding.
Journal ArticleDOI
BESPA: Software Tools for Three-Dimensional Structure Reconstruction from Single Particle Images of Proteins
TL;DR: The proposed system allows to examine structural changes and molecular complex of proteins at work, which will become a great advantage for the next generation in structural biology after static structures of proteins are all determined.