Katsuya Gomi

TL;DR: The Af293 genome sequence provides an unparalleled resource for the future understanding of this remarkable fungus and revealed temperature-dependent expression of distinct sets of genes, as well as 700 A. fumigatus genes not present or significantly diverged in the closely related sexual species Neosartorya fischeri, many of which may have roles in the pathogenicity phenotype.

TL;DR: Specific expansion of genes for secretory hydrolytic enzymes, amino acid metabolism and amino acid/sugar uptake transporters supports the idea that A. oryzae is an ideal microorganism for fermentation.

TL;DR: The genome comparison and transcriptome analysis uncovered mechanisms for effective degradation of raw materials in SSC and found the temperature reduction process empirically adopted in the traditional soy-sauce fermentation processes has been found to be important to keep strong expression of the A. oryzae-specific extracellular hydrolases.

TL;DR: Southern blot analysis revealed that transformation of Aspergillus oryzae had occurred by integration of multiple tandem copies of plasmid DNA into the host genome through non-homologous recombination.

TL;DR: Observations suggest a novel gene expression regulatory mechanism in filamentous fungi, in which exogenous thiamine controls intron splicing to regulate gene expression.