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Klaus Elenius

Researcher at University of Turku

Publications -  124
Citations -  7972

Klaus Elenius is an academic researcher from University of Turku. The author has contributed to research in topics: Receptor tyrosine kinase & ERBB4. The author has an hindex of 46, co-authored 108 publications receiving 7348 citations. Previous affiliations of Klaus Elenius include University of Kansas & Åbo Akademi University.

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Journal ArticleDOI

Amplification of HER-2 in gastric carcinoma: association with Topoisomerase IIα gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab

Minna Tanner, +12 more
- 01 Feb 2005 - 
TL;DR: HER-2/neu amplification is common in the intestinal type of gastric carcinoma, and it is associated with a poor outcome, and this hypothesis deserves to be investigated in clinical trials.
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Activation of her4 by heparin-binding egf-like growth factor stimulates chemotaxis but not proliferation

Klaus Elenius, +4 more
- 15 Mar 1997 - 
TL;DR: Heparin‐binding epidermal growth factor‐like growth factor can activate two EGF receptor subtypes, HER1 and HER4, but with different biological responses, and is a potent chemotactic factor for cells overexpressing HER4.
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Signaling via ErbB2 and ErbB3 Associates with Resistance and Epidermal Growth Factor Receptor (EGFR) Amplification with Sensitivity to EGFR Inhibitor Gefitinib in Head and Neck Squamous Cell Carcinoma Cells

Kaisa Erjala, +9 more
- 01 Jul 2006 - 
TL;DR: EGFR amplification may predict sensitivity to gefitinib in HNSCC, however, other EGFR/ErbB receptor family members than EGFR may contribute to resistance to g EFITinib.
Journal Article

Characterization of a novel cell line established from a patient with Herceptin-resistant breast cancer

Minna Tanner, +7 more
- 01 Dec 2004 - 
TL;DR: The JIMT-1 cell line provides a valuable experimental model for studies of new trastuzumab-resistance mechanisms and is phenotypically of epithelial progenitor cell origin, as evidenced by immunohistochemical positivity for both cytokeratins 5/14 and 8/18.
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Induced expression of syndecan in healing wounds.

Klaus Elenius, +5 more
- 01 Aug 1991 - 
TL;DR: The results suggest that syndecan may have a unique and important role as a cell adhesion and a growth factor-binding molecule not only during embryogenesis but also during tissue regeneration in mature tissues.