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Seija Grénman

Researcher at Turku University Hospital

Publications -  185
Citations -  8936

Seija Grénman is an academic researcher from Turku University Hospital. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 46, co-authored 179 publications receiving 7929 citations. Previous affiliations of Seija Grénman include University of Turku & Utrecht University.

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Amplification and deletion of topoisomerase IIα associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer

TL;DR: TopoIIalpha gene amplification and deletion are common in ErbB-2-amplified breast cancer and are associated with increased or decreased sensitivity to topoII inhibitors in vitro, respectively.
Journal Article

Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer.

TL;DR: The high frequency of gene amplification at chromosomal region 20q12-q13 suggests that the genes amplified therein may play a central role in the pathogenesis of sporadic and hereditary ovarian carcinoma.