K
Klaus Görlinger
Researcher at University of Duisburg-Essen
Publications - 101
Citations - 5420
Klaus Görlinger is an academic researcher from University of Duisburg-Essen. The author has contributed to research in topics: Thromboelastometry & Prothrombin complex concentrate. The author has an hindex of 37, co-authored 101 publications receiving 4696 citations. Previous affiliations of Klaus Görlinger include University of Zurich.
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Journal ArticleDOI
Point-of-care testing: a prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients.
Christian F Weber,Klaus Görlinger,Dirk Meininger,Eva Herrmann,Tobias M. Bingold,Anton Moritz,Lawrence H. Cohn,Kai Zacharowski +7 more
TL;DR: Hemostatic therapy based on POC testing reduced patient exposure to allogenic blood products and provided significant benefits with respect to clinical outcomes.
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First-line Therapy with Coagulation Factor Concentrates Combined with Point-of-Care Coagulation Testing Is Associated with Decreased Allogeneic Blood Transfusion in Cardiovascular Surgery A Retrospective, Single-center Cohort Study
Klaus Görlinger,Daniel Dirkmann,Alexander A. Hanke,Markus Kamler,Eva Kottenberg,Matthias Thielmann,Heinz Jakob,Jürgen Peters +7 more
TL;DR: First-line administration of coagulation factor concentrates combined with point-of-care testing was associated with decreased incidence of blood transfusion and thrombotic/thromboembolic events.
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Pathophysiology and Treatment of Coagulopathy in Massive Hemorrhage and Hemodilution
TL;DR: Fresh frozen plasma, platelet concentrate, and cryoprecipitate are considered the mainstay hemostatic therapies and Purified factor concentrates from recombinant synthesis are increasingly used for a rapid restoration of targeted factors.
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Reduction of Fresh Frozen Plasma Requirements by Perioperative Point-of-Care Coagulation Management with Early Calculated Goal-Directed Therapy.
Klaus Görlinger,Dietmar Fries,Daniel Dirkmann,Christian F Weber,Alexander A. Hanke,Herbert Schöchl +5 more
TL;DR: The implementation of perioperative POC coagulation management algorithms based on early, calculated, goaldirected therapy with fibrinogen concentrate and PCC is associated with a reduction in the transfusion requirements for FFP, PRBC and platelets as well as with a reduced incidence of massive transfusion.
Journal ArticleDOI
Early and individualized goal-directed therapy for trauma-induced coagulopathy
TL;DR: The concept of early, individualized and goal-directed therapy is explored in this review and the AUVA Trauma Hospital algorithm for managing trauma-induced coagulopathy is presented.