K
Koichi Sasaki
Researcher at Osaka University
Publications - 6
Citations - 5189
Koichi Sasaki is an academic researcher from Osaka University. The author has contributed to research in topics: Haematopoiesis & Myeloid. The author has an hindex of 5, co-authored 6 publications receiving 4985 citations.
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Journal ArticleDOI
Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts
Toshihisa Komori,Hideshi Yagi,Shintaro Nomura,Akira Yamaguchi,Koichi Sasaki,Kenji Deguchi,Y Shimizu,Roderick T. Bronson,Y.-H Gao,Masahiko Inada,Makoto Sato,R Okamoto,Yukihiko Kitamura,Shusaku Yoshiki,Tadamitsu Kishimoto +14 more
TL;DR: The data suggest that both intramembranous and endochondral ossification were completely blocked, owing to the maturational arrest of osteoblasts in the mutant mice, and demonstrate that Cbfa1 plays an essential role in osteogenesis.
Journal ArticleDOI
Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6.
Toshihiro Nakajima,Shigemi Kinoshita,Tatsuru Sasagawa,Koichi Sasaki,Masanobu Naruto,Tadamitsu Kishimoto,Shizuo Akira +6 more
TL;DR: It is concluded that NF-IL6 is regulated through phosphorylation by MAP kinases in response to activated ras, andutation of Thr-235 abolished the ras-dependent activation of NF- IL6.
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Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta
Koichi Sasaki,Hideshi Yagi,Roderick T. Bronson,Kumi Tominaga,Tatsuro Matsunashi,Kenji Deguchi,Yoshihiko Tani,Tadamitsu Kishimoto,Toshihisa Komori +8 more
TL;DR: It is suggested that Cbfb is essential for definitive hematopoiesis in liver, especially for the commitment to early heMatopoietic precursor cells.
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High Incidence of Chemotherapy-Induced Acral Erythema in Female Patients with non-Hodgkin's Lymphoma Treated with the Vacop-B Regimen
Hiroyasu Ogawa,Haruo Sugiyama,Yoshihiko Tani,Toshihiro Soma,Tamotsu Yamagami,Toyoshi Tatekawa,Yusuke Oji,Takeshi Kubota,Takafumi Kimura,Kazushi Inoue,Masashi Nakagawa,Koichi Sasaki,Tatsuro Matsunashi,Seigou Miyake,Tadamitsu Kishimoto +14 more
TL;DR: Seven patients with non-Hodgkin's lymphoma treated with the VACOP-B regimen utilizing granulocyte-colony-stimulating factor (G-CSF) support developed chemotherapy-induced acral erythema (CAE).
Journal ArticleDOI
Lineage- and differentiation stage-specific expression of LSM-1 (LPAP), a possible substrate for CD45, in human hematopoietic cells.
Yoshifumi Shimizu,Haruo Sugiyama,Y. Fujii,Koichi Sasaki,Kazushi Inoue,Hiroyasu Ogawa,Hiroya Tamaki,Seigou Miyake,Yusuke Oji,Toshihiro Soma,Tamotsu Yamagami,Moritoshi Hirata,K. Ikeda,T. Monden,Tadamitsu Kishimoto +14 more
TL;DR: Results showed that LSM‐1 is expressed in a lineage‐ and differentiation stage‐specific fashion in hematopoietic cells.