K
Koji Tsukamoto
Researcher at Hyogo University of Health Sciences
Publications - 19
Citations - 290
Koji Tsukamoto is an academic researcher from Hyogo University of Health Sciences. The author has contributed to research in topics: Catalysis & Nucleophile. The author has an hindex of 8, co-authored 18 publications receiving 247 citations. Previous affiliations of Koji Tsukamoto include Osaka University & Kyoto University.
Papers
More filters
Journal ArticleDOI
A coumarin-based fluorescent probe for Hg2+ and Ag+ with an N′-acetylthioureido group as a fluorescence switch
TL;DR: A coumarin-based probe with an N'-acetylthioureido group as a novel fluorescence switch is developed, in which the hydrogen bond formation between the N-hydrogen and the acetyl O atom markedly increases the susceptibility of the probe toward desulfurization by Hg(2+) and Ag(+).
Journal ArticleDOI
Radical fixation of functionalized carbon resources: alpha-sp3C-H carbamoylation of tertiary amines with aryl isocyanates.
Takehiko Yoshimitsu,Kenichi Matsuda,Kenichi Matsuda,Hiroto Nagaoka,Koji Tsukamoto,Tetsuaki Tanaka +5 more
TL;DR: The authors put forward a mechanistic proposal that is based on the isolation of borinamides produced by capturing nitrogen radical intermediates with Et3B, providing a novel one-step process for producing mepivacaine, a clinically important local anesthetic, from readily available materials.
Journal ArticleDOI
Direct construction of bicyclic heterocycles by palladium-catalyzed domino cyclization of propargyl bromides.
Hiroaki Ohno,Akinori Okano,Shohei Kosaka,Koji Tsukamoto,Miyo Ohata,Kotaro Ishihara,Hatsuo Maeda,Tetsuaki Tanaka,Nobutaka Fujii +8 more
TL;DR: The palladium-catalyzed domino cyclization of propargyl bromides having two nucleophilic functional groups is described, and the regioselectivity is completely controlled by the relative reactivity of the amine functional groups, irrespective of the position of the nucleophiles.
Journal ArticleDOI
Polyamines stabilize left-handed Z-DNA : Using X-ray crystallographic analysis, we have found a new type of polyamine (PA) that stabilizes left-handed Z-DNA
Hirofumi Ohishi,Mamiko Odoko,Kazimierz Grzeskowiak,Yoichi Hiyama,Koji Tsukamoto,Naoyoshi Maezaki,Toshimasa Ishida,Tetsuaki Tanaka,Nobuo Okabe,Keiichi Fukuyama,Da-Yang Zhou,Kazuhiko Nakatani +11 more
TL;DR: It is proved that the synthesized polyamines bind to the minor groove of Z-DNA and stabilize the conformation under various conditions, by X-ray crystallographic study, which provides a basis for clarifying B-Z transition mechanics.
Journal ArticleDOI
A Naphthalimide‐Based Cd2+ Fluorescent Probe with Carbamoylmethyl Groups Working as Chelators and PET‐Promoters under Neutral Conditions
TL;DR: Comparison of fluorescent properties between various compounds derived from 1 has demonstrated that the carbamoylmethyl groups in 1 function not only as Cd(2+) chelators but also as promoters for photoinduced electron transfer (PET) by lowering the basicity of the two tertiary amino groups.