K
Kos L
Researcher at National Institutes of Health
Publications - 2
Citations - 783
Kos L is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Neural crest & Stem cell factor. The author has an hindex of 2, co-authored 2 publications receiving 759 citations.
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Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model.
TL;DR: It is determined that premature termination of SOX10, a member of the SflV–like HMG box family of transcription factors, is responsible for absence of the neural crest derivatives in Dom mice, andSOX10 is proposed as a candidate disease gene for individuals with HSCR whose disease does not have an identified genetic origin.
Journal ArticleDOI
Hepatocyte Growth Factor/Scatter Factor-MET Signaling in Neural Crest-Derived Melanocyte Development
TL;DR: It is demonstrated that HGF/SF-MET signaling influences, but is not required for, the initial development of neural crest-derived melanocytes in vivo and in vitro.