K
Krishna G. Upadhya
Researcher at Applied Biosystems
Publications - 21
Citations - 382
Krishna G. Upadhya is an academic researcher from Applied Biosystems. The author has contributed to research in topics: Rhodamine & Fluorescence. The author has an hindex of 9, co-authored 21 publications receiving 380 citations. Previous affiliations of Krishna G. Upadhya include Life Technologies.
Papers
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Journal ArticleDOI
New energy transfer dyes for DNA sequencing
Linda G. Lee,Sandra L. Spurgeon,C. R. Heiner,Scott C. Benson,Barnett B. Rosenblum,Steven M. Menchen,Ronald J. Graham,A. Constantinescu,Krishna G. Upadhya,Jonathan M. Cassel +9 more
TL;DR: A set of four energy transfer dyes are synthesized and demonstrated their use in automated DNA sequencing and their values were reduced by 20-25% compared with the dichlororhodamine dyes alone.
Journal ArticleDOI
Fluorescent dye phosphoramidite labelling of oligonucleotides
TL;DR: A 5-carboxyfluorescein (FAM) reagent has been synthesized for use on automated DNA synthesizers, to prepare fluorescent dye labelled oligonucleotides.
Patent
Electron-deficient nitrogen heterocycle-substituted fluorescein dyes
TL;DR: In this paper, the electron-deficient nitrogen heterocycle-substituted fluorescein dyes and methods in which the dyes are conjugated to substrates and used as detection labels in molecular biology experiments are described.
Patent
Dibenzorhodamine dyes useful as fluorescent labelling agents
Scott C. Benson,Joe Y. L. Lam,Krishna G. Upadhya,Peggy Ann Radel,Weiguo Zhen,Steven M. Menchen +5 more
TL;DR: In this paper, Dibenzorhodamine compounds having structure (1) were disclosed, including nitrogen and aryl-substituted forms thereof, and intermediates useful for synthesizing such compounds were disclosed.
Patent
Reagents useful for synthesizing rhodamine-labeled oligonucleotides
TL;DR: In this article, the authors provide reagents that can be used to label synthetic oligonucleotides with rhodamine dyes or dye networks that contain rhodamines.