Kristina Langnäse

TL;DR: These findings demonstrate that it may be possible to differentiate MSC into therapeutically useful cells for clinical applications and myelinating capacity, and in some cases, single tMSC were able to myelinate more than one axon.

TL;DR: The colocalization of alpha-actin, cGMP, and cGKI isoforms provides further evidence for a significant role of the nitric oxide/cGMP pathway in the regulation of smooth muscle contractility in human prostate tissue and therefore could provide additional targets for pharmacotherapy of BPH and LUTS.

TL;DR: It is reported that murine thymocytes with a knockout mutation in α-PAK (p21-activated kinase)-interacting exchange factor (PIX), an activator of Rho GTPases, showed greatly increased motility and altered morphology in two-dimensional migration on ICAM-1.

TL;DR: The cyclic adenosine monophosphate-dependent protein kinase (cAK) is considered a key protein in the control of smooth muscle tone in the cardiovascular system as discussed by the authors.

TL;DR: The expression of cAK and cGKIbeta in relation to VIP, PGP 9.5 in human vaginal tissue demonstrates the significance of both the cAMP and GMP pathway in the control of human vaginal vascular and nonvascular smooth muscle.