K
Kwang Hyuck Lee
Researcher at Johns Hopkins University
Publications - 1
Citations - 2008
Kwang Hyuck Lee is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Gene silencing & Transactivation. The author has an hindex of 1, co-authored 1 publications receiving 1925 citations.
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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
Tsung Cheng Chang,Erik A. Wentzel,Oliver A. Kent,Kalyani Ramachandran,Michael Mullendore,Kwang Hyuck Lee,Georg Feldmann,Munekazu Yamakuchi,Marcella Ferlito,Charles J. Lowenstein,Dan E. Arking,Michael A. Beer,Anirban Maitra,Joshua T. Mendell +13 more
TL;DR: It is demonstrated that microRNAs (miRNAs) are important components of the p53 transcriptional network and miR-34a-responsive genes are highly enriched for those that regulate cell-cycle progression, apoptosis, DNA repair, and angiogenesis.