Kyung-Soo Chang

TL;DR: It is demonstrated that apoE is required forHCV virion infectivity and production, suggesting that HCV virions are assembled as apOE-enriched lipoprotein particles, and identified apo E as a novel target for discovery and development of antiviral drugs and monoclonal antibodies to suppress HCVvirion formation and infection.

TL;DR: It is demonstrated that a subgenomic RNA replicon of genotype 2a HCV replicated efficiently in mouse embryonic fibroblasts (MEFs), as determined by cell colony formation efficiency and the detection of HCV proteins and both positive- and negative-strand RNAs.

TL;DR: It is reported here that SAA inhibited hepatitis C virus (HCV) infection in cultured cells, suggesting that S AA functions as part of the host innate immune defense mechanisms against HCV infection in humans.

TL;DR: It is demonstrated that the phosphorylated form of PTB is associated with the membrane-bound HCV replication complex and is required for efficient HCV RNA replication in the cell.

TL;DR: An analysis of antimicrobial resistance and virulence gene pattern combined with RAPD indicated that a certain P. multocida strain appeared to be genetically identical, implying the persistence of the strain within a single farm.