Institution
Seoul Metropolitan Government
Government•Seoul, South Korea•
About: Seoul Metropolitan Government is a government organization based out in Seoul, South Korea. It is known for research contribution in the topics: Population & Medicine. The organization has 1278 authors who have published 1927 publications receiving 23196 citations.
Topics: Population, Medicine, Odds ratio, Hazard ratio, Diabetes mellitus
Papers published on a yearly basis
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TL;DR: There were significant differences in the elasticity values of benign and malignant masses as well as invasive and intraductal cancers with SWE, suggesting that SWE has the potential to aid in the differentiation of harmless and harmful breast lesions.
Abstract: Shear wave elastography (SWE) is an emerging technique which can obtain quantitative elasticity values in breast disease. We therefore evaluated the diagnostic performance of SWE for the differentiation of breast masses compared with conventional ultrasound (US). Conventional US and SWE were performed by three experienced radiologists for 158 consecutive women who had been scheduled for US-guided core biopsy or surgical excision in 182 breast masses (89 malignancies and 93 benign; mean size, 1.76 cm). For each lesion, quantitative elasticity was measured in terms of the Young’s modulus (in kilopascals, kPa) with SWE, and BI-RADS final categories were assessed with conventional US. The mean elasticity values were significantly higher in malignant masses (153.3 kPa ± 58.1) than in benign masses (46.1 kPa ± 42.9), (P < 0.0001). The average mean elasticity values of invasive ductal (157.5 ± 57.07) or invasive lobular (169.5 ± 61.06) carcinomas were higher than those of ductal carcinoma in situ (117.8 kPa ± 54.72). The average mean value was 49.58 ± 43.51 for fibroadenoma, 35.3 ± 31.2 for fibrocystic changes, 69.5 ± 63.2 for intraductal papilloma, and 149.5 ± 132.4 for adenosis or stromal fibrosis. The optimal cut-off value, yielding the maximal sum of sensitivity and specificity, was 80.17 kPa, and the sensitivity and specificity of SWE were 88.8% (79 of 89) and 84.9% (79 of 93). The area under the ROC curve (Az value) was 0.898 for conventional US, 0.932 for SWE, and 0.982 for combined data. In conclusion, there were significant differences in the elasticity values of benign and malignant masses as well as invasive and intraductal cancers with SWE. Our results suggest that SWE has the potential to aid in the differentiation of benign and malignant breast lesions.
306 citations
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TL;DR: Low muscle mass was found to be associated with histological severity in non-alcoholic fatty liver disease, and sarcopenia was significantly associated with non- alcoholic steatohepatitis and significant fibrosis, independent of obesity, inflammation, and insulin resistance.
292 citations
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TL;DR: The prodromal symptoms of COVID-19 were mild and most patients did not have limitations of daily activity, and these findings could be plausible explanations for the easy and rapid spread of SARS-CoV-2 in the community.
Abstract: Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected pneumonia emerged in Wuhan, China in December 2019. In this retrospective multicenter study, we investigated the clinical course and outcomes of novel coronavirus disease 2019 (COVID-19) from early cases in Republic of Korea. Methods All of the cases confirmed by real time polymerase chain reaction were enrolled from the 1st to the 28th patient nationwide. Clinical data were collected and analyzed for changes in clinical severity including laboratory, radiological, and virologic dynamics during the progression of illness. Results The median age was 40 years (range, 20-73 years) and 15 (53.6%) patients were male. The most common symptoms were cough (28.6%) and sore throat (28.6%), followed by fever (25.0%). Diarrhea was not common (10.7%). Two patients had no symptoms. Initial chest X-ray (CXR) showed infiltration in 46.4% of the patients, but computed tomography scan confirmed pneumonia in 88.9% (16/18) of the patients. Six patients (21.4%) required supplemental oxygen therapy, but no one needed mechanical ventilation. Lymphopenia was more common in severe cases. Higher level of C-reactive protein and worsening of chest radiographic score was observed during the 5-7 day period after symptom onset. Viral shedding was high from day 1 of illness, especially from the upper respiratory tract (URT). Conclusion The prodromal symptoms of COVID-19 were mild and most patients did not have limitations of daily activity. Viral shedding from URT was high from the prodromal phase. Radiological pneumonia was common from the early days of illness, but it was frequently not evident in simple CXR. These findings could be plausible explanations for the easy and rapid spread of SARS-CoV-2 in the community.
272 citations
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TL;DR: Patients with NAFLD are at increased risk for coronary atherosclerosis independent of classical coronary risk factors, including visceral adiposity, according to this data, which suggest thatNAFLD might be an independent risk factor for coronary artery disease.
272 citations
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Soonchunhyang University1, Catholic University of Korea2, Yonsei University3, University of Ulsan4, Ewha Womans University5, Inha University6, Ajou University7, Seoul Metropolitan Government8, Korea University9, Samsung Medical Center10, Kyung Hee University11, Inje University12, Asan Medical Center13
TL;DR: Efforts should be made to increase awareness, detection, and comprehensive management of diabetes to reduce diabetes-related morbidity and mortality and confirms that diabetes is as an important public health problem.
Abstract: Background: The objective of this study was to investigate the prevalence, management, and comorbidities of diabetes among Korean adults aged 30 years and older.
Methods: This study used 2013 to 2016 data from the Korea National Health and Nutrition Examination Survey, a nationally-representative survey of the Korean population. Diabetes was defined as fasting glucose ≥126 mg/dL, current use of antidiabetic medication, a previous history of diabetes, or glycosylated hemoglobin (HbA1c) ≥6.5%.
Results: In 2016, 14.4% (approximately 5.02 million) of Korean adults had diabetes. The prevalence of impaired fasting glucose was 25.3% (8.71 million). From 2013 to 2016, the awareness, control, and treatment rates for diabetes were 62.6%, 56.7%, and 25.1%, respectively. People with diabetes had the following comorbidities: obesity (50.4%), abdominal obesity (47.8%), hypertension (55.3%), and hypercholesterolemia (34.9%). The 25.1%, 68.4%, and 44.2% of people with diabetes achieved HbA1c <6.5%, blood pressure <140/85 mm Hg, and low density lipoprotein cholesterol <100 mg/dL. Only 8.4% of people with diabetes had good control of all three targets.
Conclusion: This study confirms that diabetes is as an important public health problem. Efforts should be made to increase awareness, detection, and comprehensive management of diabetes to reduce diabetes-related morbidity and mortality.
241 citations
Authors
Showing all 1291 results
Name | H-index | Papers | Citations |
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J. S. H. Lee | 90 | 1068 | 44886 |
Patrick Waters | 67 | 216 | 20716 |
Wan Beom Park | 45 | 261 | 6981 |
Donghee Kim | 42 | 256 | 7769 |
Jun-Young Lee | 40 | 298 | 5776 |
Jung Min Chang | 36 | 158 | 4404 |
Won Kim | 35 | 270 | 5135 |
Eun Young Lee | 35 | 192 | 4652 |
Seong Yeon Kim | 33 | 125 | 3072 |
Joo Myung Lee | 32 | 249 | 3814 |
Sang Wan Kim | 32 | 114 | 2771 |
Yu Kyeong Kim | 32 | 173 | 3497 |
Heesun Chung | 31 | 135 | 2808 |
Do Sun Lim | 31 | 232 | 5258 |
Kyoung Jun Song | 31 | 198 | 3297 |