L
L. de Jong
Researcher at University of Amsterdam
Publications - 28
Citations - 2759
L. de Jong is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Nuclear matrix & Cell nucleus. The author has an hindex of 21, co-authored 28 publications receiving 2718 citations. Previous affiliations of L. de Jong include Centre national de la recherche scientifique.
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Fluorescent labeling of nascent RNA reveals transcription by RNA polymerase II in domains scattered throughout the nucleus
TL;DR: The distribution of sites of transcription by RNA polymerase II (RPII) is examined by labeling nascent RNA with 5-bromouridine 5'-triphosphate, in vitro and in vivo, and there is no correlation between intensely labeled SC-35 domains and sites of pre-mRNA synthesis.
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The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion.
Marcel Koken,Francine Puvion-Dutilleul,Marie-Claude Guillemin,A. Viron,G. Linares-Cruz,Nico Stuurman,L. de Jong,C. Szostecki,Fabien Calvo,Christine Chomienne +9 more
TL;DR: In this article, the authors showed that PML, a protein involved in the translocation of acute promyelocytic leukaemia (APL), is specifically bound to a nuclear body.
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A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies
TL;DR: It is concluded that mAb 5E10 recognizes discrete nuclear substructures, most likely nuclear bodies, in the interphase nucleus.
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Nuclear distribution of transcription factors in relation to sites of transcription and rna polymerase ii
TL;DR: The results indicate that many of the transcription factor-rich nuclear domains are not actively involved in transcription, and may represent incomplete transcription initiation complexes, inhibitory complexes, or storage sites.
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The nuclear matrix from cells of different origin. Evidence for a common set of matrix proteins.
TL;DR: In this paper, the protein composition of the nuclear matrix isolated from several murine embryonal carcinoma cells and mature tissues by two-dimensional gel electrophoresis was compared, and a limited set of polypeptides common to all mouse cell types was identified.