L.Dennis Smith

TL;DR: It is suggested that the steroid acts at or near the surface to cause the production of a second effector which, when accumulated to a sufficient level in the oocyte, induces the observable events associated with maturation.

TL;DR: Examination of two-dimensional gels showed minimal changes in the types of polypeptides synthesized from control and progesterone- and MPF-matured oocytes, but there was an overall increase in the synthesis of individual polypePTides during progester one and MPf-induced maturation.

TL;DR: Displacement and competition experiments between four different mRNAs indicate that injected messages are distributed to two translational compartments, membrane-bound and free, and that this occurs either prior to the initiation of translation or involves message-specific factors.

TL;DR: The amphibian lampbrush chromosome stage oocyte nucleus synthesizes and transports to the cytoplasm poly(A) RNAs that, are similar in structure and sequence content to the maternal poly(B) RNA stored in the oocyte at the termination of oogenesis, thereby maintaining an approximately constant steady state throughout oogenesis.

TL;DR: It is suggested that theophylline may exert its inhibitory effects on maturation either by reducing rates of protein synthesis or possibly through effects at the oocyte surface.