Lalit Kumar

TL;DR: The possibility of exploring the role of circRNAs in the context of the central nervous system (CNS) and age-associated neurodegenerative diseases is reviewed.

TL;DR: Employing transgenic C. elegans model of PD, RNase R-mediated cleavage of linear RNA followed by divergent primer-based amplifications are used towards identifying circzip-2, a novel circRNA molecule, which is synthesized from functionally important gene zip-2.

TL;DR: The first dual colorimetric and ratiometric fluorescent probe naphtho[2,1-b][1,10]phenanthroline for selective and 'direct' visualization of labile iron(III) pools in a multicellular organism, Caenorhabditis elegans is reported.

TL;DR: It is concluded that introduction of the pharmacophore responsible for spermicidal activity into a proven anti-trichomonas structure may lead to a potent dual function microbicide better and safer than N-9.

TL;DR: The study revealed that incorporation of carbodithioic acid residue directly into fluoxetine structure leads to compounds with better antifungal and anti-Trichomonas activities, and N-methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]carbodithIOic acid S-(2-pyrrolidino-ethyl) ester (14) has shown better profile than both fluoxettine