Lambert Zijp

TL;DR: An alternative respiratory correlated CBCT procedure is developed that reduces respiration induced geometrical uncertainties, enabling safe delivery of 4D radiotherapy such as gated radiotherapy with small margins.

TL;DR: Implementing matched CT-FDG-PET and adapted delineation protocol and software reduced observer variation in lung cancer delineation significantly with respect to CT only, but the remaining observer variation was still large compared with other geometric uncertainties (setup variation and organ motion).

TL;DR: The use of conformal tangential fields decreases the NTCP for late cardiac toxicity on average by 30% compared to using rectangular fields, while the tangential IMRT technique can further reduce this value by an additional 50%.

TL;DR: It is concluded that CBCT scans are suitable for online and offline position verification of the prostate, as long as the amount of nonstationary gas is limited.

TL;DR: A method to quantify shape variation of organs with a complex shape and applied it to a GTV consisting of prostate and seminal vesicles, which is a valid approximation in image-guided radiotherapy of prostate cancer to correct only for setup errors and organ motion.