L
Lan Juan Zhao
Researcher at Tulane University
Publications - 32
Citations - 1782
Lan Juan Zhao is an academic researcher from Tulane University. The author has contributed to research in topics: Single-nucleotide polymorphism & Candidate gene. The author has an hindex of 21, co-authored 32 publications receiving 1675 citations. Previous affiliations of Lan Juan Zhao include University of Missouri–Kansas City & Creighton University Medical Center.
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Journal ArticleDOI
Relationship of obesity with osteoporosis.
Lan Juan Zhao,Yong Jun Liu,Pengyuan Liu,James A. Hamilton,Robert R. Recker,Hong-Wen Deng,Hong-Wen Deng,Hong-Wen Deng +7 more
TL;DR: The relationship between obesity and osteoporosis is reevaluate by accounting for the mechanical loading effects of total body weight on bone mass and the phenotypic correlation between fat mass and fat mass was negative, suggesting increasing fat mass may not have a beneficial effect on bonemass.
Journal ArticleDOI
Comprehensive association analysis of nine candidate genes with serum 25-hydroxy vitamin D levels among healthy Caucasian subjects
Fengxiao Bu,Laura A.G. Armas,Joan M. Lappe,Yu Zhou,Guimin Gao,Hong Wei Wang,Robert R. Recker,Lan Juan Zhao +7 more
TL;DR: Nine important genes in vitamin D metabolic pathways are screened using 49 single nucleotide polymorphism (SNP) markers and results suggest that the CYP2R1 and GC genes may contribute to the variation of serum 25(OH)D levels in healthy populations.
Journal ArticleDOI
Polymorphisms of the low‐density lipoprotein receptor‐related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family‐based association study
Yan-Fang Guo,Dong Hai Xiong,Hui Shen,Lan Juan Zhao,Peng Xiao,Yan Guo,Wei Wang,Tie-Lin Yang,Robert R. Recker,Hong-Wen Deng,Hong-Wen Deng +10 more
TL;DR: Intronic variants of the LRP5 gene are markedly associated with obesity, and it is hypothesised that such an association may be due to the role of L RP5 in the WNT signalling pathway or lipid metabolism.
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Robust and Comprehensive Analysis of 20 Osteoporosis Candidate Genes by Very High-Density Single-Nucleotide Polymorphism Screen Among 405 White Nuclear Families Identified Significant Association and Gene–Gene Interaction
Dong Hai Xiong,Hui Shen,Lan Juan Zhao,Peng Xiao,Tie-Lin Yang,Yan Guo,Wei Wang,Yan Fang Guo,Yong Jun Liu,Robert R. Recker,Hong-Wen Deng,Hong-Wen Deng,Hong-Wen Deng +12 more
TL;DR: This work screened 20 “novel” osteoporosis candidate genes using a set of high‐density SNPs in a large family‐based study and led to the prioritization of those osteopOrosis genes and the detection of gene–gene interactions.
Journal ArticleDOI
Genomic regions identified for BMD in a large sample including epistatic interactions and gender-specific effects
Peng Xiao,Hui Shen,Yan Fang Guo,Yan Fang Guo,Dong Hai Xiong,Yao Zhong Liu,Yong Jun Liu,Lan Juan Zhao,Jirong Long,Yan Guo,Yan Guo,Robert R. Recker,Hong-Wen Deng,Hong-Wen Deng,Hong-Wen Deng +14 more
TL;DR: A genome‐wide linkage scan was conducted using a large white sample to identify QTLs for BMD and gender‐specific subgroups, as well as significant epistatic interactions underlying BMD variations.