Laura B. Talarico

TL;DR: Variations in antiviral activity of the polysaccharides depending on the viral serotype and the host cell may be ascribed to differences in the virus-cell interaction leading to virus entry.

TL;DR: A significant protection against a murine vaginal infection with HSV-2 was afforded by topical treatment with the sulfated galactans, and the mode of action of these compounds could be mainly ascribed to an inhibitory effect on virus adsorption.

TL;DR: The dual sites of action of an HS-like molecule suggest that, at least in monkey kidney and human hepatic cells, the HS residues in the cell membrane appear to act as mediators for DENV-2 entry, an interesting alternative target for flavivirus therapy.

TL;DR: Chemical and spectroscopic methods showed that the major KCl-precipitated galactans from Meristiella gelidium (Solieriaceae) are iota/kappa/nu-hybrid carrageenans with the former one in higher proportion, with a value high enough to consider thisCarrageenan as a promising agent to be evaluated for the treatment of genital HSV-2 infections.

TL;DR: Essential oils obtained from eight aromatic plants of San Luis Province, Argentina, were screened for virucidal activity against herpes simplex virus type 1, Junin virus (JUNV) and dengue virus type 2 (DEN‐2) and the most potent inhibition was observed with the essential oil of Lippia junelliana and Lippi turbinata against JUNV.