Laura D. Locati

TL;DR: The molecular and clinical results are in agreement with previous findings but provide additional information into the biologic mechanisms involved in HR-HPV oropharyngeal cancer in comparison to HPV-negative tumors.

TL;DR: Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; Department of Head and Neck Oncology, Gustave Roussy, Villejuif; Université Paris Saclay, Villeroy-sur-Sierre, France; and Department of Nuclear Medicine and Endocrine Oncological Sciences and Public Health, University of Brescia.

TL;DR: Surgery, irradiation or re-irradiation are treatment options for local relapse, whereas radical neck dissection is indicated for regional relapses, and the employment of anti-androgen therapy is indicated.

TL;DR: Although the objective response rate was low, a significant proportion of MTC patients (81%) achieved stable disease while receiving motesanib, and motesanIB trough concentrations were lower compared with differentiated thyroid cancer patients from the same study.

TL;DR: In RMSGCs further evaluations of EGFR targeting agents are advisable and should take place by appropriate tumor biological selection, differentiating ACC from non-ACC.