L
Laura de Magistris
Researcher at Seconda Università degli Studi di Napoli
Publications - 39
Citations - 3109
Laura de Magistris is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Intestinal permeability & Gastrin. The author has an hindex of 24, co-authored 39 publications receiving 2749 citations. Previous affiliations of Laura de Magistris include Aarhus University & Sapienza University of Rome.
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Journal ArticleDOI
Zonulin Upregulation Is Associated With Increased Gut Permeability in Subjects With Type 1 Diabetes and Their Relatives
Anna Sapone,Laura de Magistris,Michelle Pietzak,Maria Grazia Clemente,Amit Tripathi,Francesco Cucca,Rosanna Lampis,Deborah Kryszak,Maria Cartenì,Maddalena Generoso,Dario Iafusco,Francesco Prisco,Francesca Laghi,Gabriele Riegler,Romano Carratù,Debra Counts,Alessio Fasano +16 more
TL;DR: Zonulin upregulation seems to precede the onset of the disease, providing a possible link between increased intestinal permeability, environmental exposure to non–self antigens, and the development of autoimmunity in genetically susceptible individuals.
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Alterations of the intestinal barrier in patients with autism spectrum disorders and in their first-degree relatives.
Laura de Magistris,Valeria Familiari,Antonio Pascotto,Anna Sapone,Alessandro Frolli,Patrizia Iardino,Maria Cartenì,Mario De Rosa,Ruggiero Francavilla,Gabriele Riegler,Roberto Militerni,Carmela Bravaccio +11 more
TL;DR: It is indicated that measuring IPT could help to identify a subgroup of patients with autism who could benefit from a gluten-free diet and indicate the presence of an intestinal (tight-junction linked) hereditary factor in the families of subjects with autism.
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Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity
Anna Sapone,Anna Sapone,Karen M. Lammers,Vincenzo Casolaro,Vincenzo Casolaro,Marcella Cammarota,Maria Teresa Giuliano,Mario De Rosa,Rosita Stefanile,Giuseppe Mazzarella,Carlo Tolone,Maria Itria Russo,Pasquale Esposito,Franca Ferraraccio,Maria Cartenì,Gabriele Riegler,Laura de Magistris,Alessio Fasano +17 more
TL;DR: This study shows that the two gluten-associated disorders, CD and GS, are different clinical entities, and it contributes to the characterization of GS as a condition associated with prevalent gluten-induced activation of innate, rather than adaptive, immune responses in the absence of detectable changes in mucosal barrier function.
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Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria
Carlo Catassi,Luca Elli,Bruno Bonaz,Gerd Bouma,Antonio Carroccio,Gemma Castillejo,Christophe Cellier,Fernanda Cristofori,Laura de Magistris,Jernej Dolinsek,Walburga Dieterich,Ruggiero Francavilla,Marios Hadjivassiliou,Wolfgang Holtmeier,Ute Körner,Daniel A. Leffler,Knut E.A. Lundin,Giuseppe Mazzarella,Chris J. J. Mulder,Nicoletta Pellegrini,Kamran Rostami,David S Sanders,Gry Irene Skodje,Detlef Schuppan,Reiner Ullrich,Umberto Volta,Marianne Williams,Victor F. Zevallos,Yurdagül Zopf,Alessio Fasano +29 more
TL;DR: Experts’ recommendations on how the diagnostic protocol should be performed for the confirmation of non-Celiac Gluten Sensitivity are reported, to help the clinician to reach a firm and positive diagnosis of NCGS.
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The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update
Carlo Catassi,Armin Alaedini,Christian Bojarski,Bruno Bonaz,Gerd Bouma,Antonio Carroccio,Gemma Castillejo,Laura de Magistris,Walburga Dieterich,Diana Di Liberto,Luca Elli,Alessio Fasano,Marios Hadjivassiliou,Matthew Kurien,Elena Lionetti,Chris J. J. Mulder,Kamran Rostami,Anna Sapone,Katharina Anne Scherf,Detlef Schuppan,Nick Trott,Umberto Volta,Victor F. Zevallos,Yurdagül Zopf,David S Sanders +24 more
TL;DR: Clinicians are provided with an update that directly impacts on the management of a subgroup of their IBS patients whose symptoms are triggered by wheat ingestion.