L
Laura E J Peeters
Researcher at Erasmus University Rotterdam
Publications - 21
Citations - 239
Laura E J Peeters is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Medicine & Blood pressure. The author has an hindex of 5, co-authored 10 publications receiving 149 citations. Previous affiliations of Laura E J Peeters include University of Edinburgh.
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Journal ArticleDOI
Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury
A. D. B. Vliegenthart,Jonathan M Shaffer,Joanna I. Clarke,Laura E J Peeters,Andrea Caporali,D. N. Bateman,David M. Wood,David M. Wood,Paul I. Dargan,Paul I. Dargan,D G Craig,Joanna Moore,Alexandra I. Thompson,Neil C. Henderson,David J. Webb,Jack Sharkey,D.J. Antoine,B.K. Park,Matthew A. Bailey,Eric Lader,Kenneth J. Simpson,James W. Dear +21 more
TL;DR: Profiling of acetaminophen toxicity identified multiple miRNAs that report acute liver injury and potential biomarkers of drug-induced kidney injury that are associated with human kidney dysfunction.
Journal ArticleDOI
Personalized immunosuppression in elderly renal transplant recipients
TL;DR: There is an urgent need to perform clinical trials investigating novel immunosuppressive regimens in conjunction with biomarker studies in this specific population of elderly patients, according to an unmet need in transplantation medicine.
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Clinical Applicability of Monitoring Antihypertensive Drug Levels in Blood.
Laura E J Peeters,Lida Feyz,Eric Boersma,Joost Daemen,Teun van Gelder,Birgit C. P. Koch,Jorie Versmissen +6 more
TL;DR: The Cplasma of the 8 antihypertensive drugs in this study show a large interindividual difference, and therefore, low plasma concentrations do not necessarily mean nonadherence, and DBS is a reliable and convenient method to assess nonadherent drugs in clinical practice.
Journal ArticleDOI
Clinical Validation of a Dried Blood Spot Assay for 8 Antihypertensive Drugs and 4 Active Metabolites.
Laura E J Peeters,Lida Feyz,Edon Hameli,Tom C. Zwart,Soma Bahmany,Joost Daemen,Teun van Gelder,Jorie Versmissen,Birgit C. P. Koch +8 more
TL;DR: The DBS assay is a suitable method to detect drug non-adherence, but with the exception of canrenone, the interchangeable use of plasma and DBS sampling to interpret drug quantities should be avoided.
Journal ArticleDOI
Drug nonadherence is a common but often overlooked cause of hypertensive urgency and emergency at the emergency department.
Naomi Overgaauw,Jelmer Alsma,Anniek Brink,Edon Hameli,Soma Bahmany,Laura E J Peeters,Anton H. van den Meiracker,Stephanie C. E. Schuit,Birgit C. P. Koch,Jorie Versmissen +9 more
TL;DR: Hypertensive urgency and hypertensive emergency are common health problems resulting in frequent emergency department admissions and workup of patients with a hypertensive urgency should include an assessment of drug adherence to optimize treatment strategy.