Laura J. Macdougall

TL;DR: The preparation of biocompatible and biodegradable poly(ε-caprolactone) 1D and 2D micelles in water and alcoholic solvents via crystallization-driven self-assembly is reported, achieving precise control over 1D nanostructures in water, an essential feature for any relevant biological application.

TL;DR: The photoclick chemistry as discussed by the authors is a collection of click reactions that are performed via the application of light, and it has had diverse impact over a broad range of chemical and biological research due to the spatiotemporal control, high selectivity, and excellent product yields afforded by the combination of light and click chemistry.

TL;DR: It is demonstrated that the nucleophilic thiol-yne click reaction presents a highly efficient chemistry for forming robust high water content (ca. 90%) hydrogel materials with tunable stiffness and mechanical properties.

TL;DR: This work describes a simple and effective way to control the swelling and degradation rate of nucleophilic thiol–yne poly(ethylene glycol) (PEG) hydrogel networks using two straightforward routes: using multiarm alkyne and thiol terminated PEG precursors or introducing a thermoresponsive unit into the PEG network while maintaining their robust mechanical properties.

TL;DR: The hierarchical nature of the self-assembly process in water was characterised by a combination of electron microscopy imaging and small-angle X-ray scattering, revealing a porous network of entangled nanofibres composed by the aggregation of several cyclic peptide nanotubes.