Nonswelling Thiol–Yne Cross-Linked Hydrogel Materials as Cytocompatible Soft Tissue Scaffolds
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TLDR
This work describes a simple and effective way to control the swelling and degradation rate of nucleophilic thiol–yne poly(ethylene glycol) (PEG) hydrogel networks using two straightforward routes: using multiarm alkyne and thiol terminated PEG precursors or introducing a thermoresponsive unit into the PEG network while maintaining their robust mechanical properties.About:
This article is published in Biomacromolecules.The article was published on 2018-05-14 and is currently open access. It has received 60 citations till now.read more
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3D Extracellular Matrix Mimics: Fundamental Concepts and Role of Materials Chemistry to Influence Stem Cell Fate
TL;DR: This review will present the fundamentals of ECM, cover the chemical and structural features of the scaffolds used to generate ECM mimics, discuss the nature of the signaling biomolecules required and exploited to generate bioresponsive cell microenvironments able to induce a specific cell fate, and highlights the syn-thetic strategies involved to create functional 3D ECm mimics.
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Sulfur Chemistry in Polymer and Materials Science
Hatice Mutlu,Ezgi Berfin Ceper,Xiaohui Li,Jingmei Yang,Jingmei Yang,Wenyuan Dong,Mehmet Murat Ozmen,Patrick Theato +7 more
TL;DR: An overview of strategies and developments used over the last 5 years to reinforce the importance of the sulfur functional group in modern polymer and materials science is presented.
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Antibacterial hydrogel coating: Strategies in surface chemistry.
TL;DR: The chemical methods used to fix the antibacterial hydrogel layer on the substrate are summarized, which include surface-initiated graft crosslinking polymerization, anchoring the hydrogelslayer on the surface duringCrosslinking, and chemical crossl linking of layer-by-layer coating.
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Covalently Crosslinked Hydrogels via Step-Growth Reactions: Crosslinking Chemistries, Polymers, and Clinical Impact.
TL;DR: In this article, a review of crosslinking chemistries and polymers commonly used for preparing translatable hydrogels are outlined and their performance in biological systems is summarized, and examples of effective polymer/crosslinking chemistry combinations that have yielded clinically approved hydrogel products are specifically highlighted.
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Swelling-strengthening hydrogels by embedding with deformable nanobarriers.
Feng Wu,Yan Pang,Jinyao Liu +2 more
TL;DR: A swelling-strengthening phenomenon of polymer materials achieved by a bioinspired strategy involving Liposomal membrane nanobarriers embedded in a crosslinked network to regulate transmembrane transport is described.
References
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Hydrogels in regenerative medicine
Brandon V. Slaughter,Shahana S. Khurshid,Omar Z. Fisher,Ali Khademhosseini,Nicholas A. Peppas +4 more
TL;DR: The properties of hydrogels that are important for tissue engineering applications and the inherent material design constraints and challenges are discussed.