L
Laura K. Moore
Researcher at Northwestern University
Publications - 18
Citations - 727
Laura K. Moore is an academic researcher from Northwestern University. The author has contributed to research in topics: Drug delivery & Medicine. The author has an hindex of 9, co-authored 14 publications receiving 596 citations. Previous affiliations of Laura K. Moore include Duke University & University of California, San Francisco.
Papers
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Journal ArticleDOI
Diamond nanogel-embedded contact lenses mediate lysozyme-dependent therapeutic release.
TL;DR: A nanodiamond (ND)-embedded contact lens capable of lysozyme-triggered release of TM for sustained therapy is presented and it is found that ND-embedded lenses composed of enzyme-cleavable polymers allow for controlled and sustained release ofTM in the presence of Lysozyme.
Journal ArticleDOI
Biocompatibility Assessment of Detonation Nanodiamond in Non-Human Primates and Rats Using Histological, Hematologic, and Urine Analysis.
Laura K. Moore,Junyu Yang,Thanh T. Ha Lan,Eiji Osawa,Dong-Keun Lee,William D. Johnson,Jianzhong Xi,Edward Kai-Hua Chow,Dean Ho +8 more
TL;DR: Results from a DND biocompatibility study in both non-human primates and rats indicate that NDs are well-tolerated at clinically relevant doses.
Journal ArticleDOI
Diamond-lipid hybrids enhance chemotherapeutic tolerance and mediate tumor regression.
TL;DR: Epidermal growth factor receptor-targeted NDLPs are highly biocompatible particles that provide cell-specific imaging, promote tumor retention of ND-complexes, prevent epirubicin toxicities and mediate regression of triple negative breast cancers.
Journal ArticleDOI
A Robust Monte Carlo Model for the Extraction of Biological Absorption and Scattering In Vivo
Janelle E. Bender,Karthik Vishwanath,Laura K. Moore,J. Brown,Vivide Tuan-Chyan Chang,Gregory M. Palmer,Nirmala Ramanujam +6 more
TL;DR: The robustness of the toolbox for quantifying physiologically relevant parameters from turbid tissue-like media is assessed and an assessment on which reference phantom serves as the best calibration standard to enable accurate extraction of the absorption and scattering properties of the target sample is included.
Journal ArticleDOI
Comprehensive interrogation of the cellular response to fluorescent, detonation and functionalized nanodiamonds
Laura K. Moore,Valéria Grobárová,Helen Shen,Han Bin Man,Júlia Mičová,Júlia Mičová,Miroslav Ledvina,Miroslav Ledvina,Jan Stursa,Milos Nesladek,Milos Nesladek,Anna Fišerová,Anna Fišerová,Dean Ho,Dean Ho +14 more
TL;DR: A comprehensive analysis of the cellular compatibility of an array of nanodiamond subtypes and surface functionalization strategies demonstrates that NDs are well tolerated by multiple cell types at both functional and gene expression levels.