L
Lauren E. Kelly
Researcher at University of Manitoba
Publications - 51
Citations - 3232
Lauren E. Kelly is an academic researcher from University of Manitoba. The author has contributed to research in topics: Clinical trial & Randomized controlled trial. The author has an hindex of 18, co-authored 47 publications receiving 2531 citations. Previous affiliations of Lauren E. Kelly include Boston Children's Hospital & London Health Sciences Centre.
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Journal ArticleDOI
A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19.
David R. Boulware,Matthew F Pullen,Ananta S. Bangdiwala,Katelyn A Pastick,Sarah M Lofgren,Elizabeth C Okafor,Caleb P Skipper,Alanna A Nascene,Melanie R. Nicol,Mahsa Abassi,Nicole W. Engen,Matthew P. Cheng,Derek LaBar,Sylvain A. Lother,Lauren J. MacKenzie,Glen Drobot,Nicole Marten,Ryan Zarychanski,Lauren E. Kelly,Ilan S. Schwartz,Emily G. McDonald,Radha Rajasingham,Todd C. Lee,Kathy H. Hullsiek +23 more
TL;DR: After high-risk or moderate-risk exposure to Covid-19, hydroxychloroquine did not prevent illness compatible with Covid -19 or confirmed infection when used as postexposure prophylaxis within 4 days after exposure.
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Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19 : A Randomized Trial.
Caleb P Skipper,Katelyn A Pastick,Nicole S Engen,Ananta S Bangdiwala,Mahsa Abassi,Sarah M Lofgren,Darlisha A. Williams,Elizabeth C Okafor,Matthew F Pullen,Melanie R. Nicol,Alanna A Nascene,Katherine Huppler Hullsiek,Matthew P. Cheng,Darlette Luke,Sylvain A. Lother,Lauren J. MacKenzie,Glen Drobot,Lauren E. Kelly,Ilan S. Schwartz,Ryan Zarychanski,Emily G. McDonald,Todd C. Lee,Radha Rajasingham,David R. Boulware +23 more
TL;DR: This randomized, double-blind, placebo-controlled trial evaluated effects of oral hydroxychloroquine on symptoms and disease severity in adult outpatients with early COVID-19.
Journal ArticleDOI
More Codeine Fatalities After Tonsillectomy in North American Children
Lauren E. Kelly,Michael J. Rieder,John N. van den Anker,Becky Malkin,Colin J. D. Ross,Michael Neely,Bruce Carleton,Bruce Carleton,Michael R. Hayden,Parvaz Madadi,Gideon Koren,Gideon Koren +11 more
TL;DR: Three additional fatal or life-threatening cases from North America demonstrate that analgesia with codeine or other opioids that use the CYP2D6 pathway after adenotonsillectomy may not be safe in young children with obstructive sleep apnea syndrome.
Journal ArticleDOI
Review: Hydroxychloroquine and chloroquine for treatment of SARS-CoV-2 (COVID-19)
Katelyn A Pastick,Elizabeth C Okafor,Fan Wang,Sarah M Lofgren,Caleb P Skipper,Melanie R. Nicol,Matthew F Pullen,Radha Rajasingham,Emily G. McDonald,Todd C. Lee,Ilan S. Schwartz,Lauren E. Kelly,Sylvain A. Lother,Oriol Mitjà,Emili Letang,Mahsa Abassi,David R. Boulware +16 more
TL;DR: A rapid narrative review and call for additional randomized controlled trial evidence prior to the widespread incorporation of hydroxychloroquine and chloroquine into national and international treatment guidelines are called for.
Journal ArticleDOI
Morphine or Ibuprofen for Post-Tonsillectomy Analgesia: A Randomized Trial
Lauren E. Kelly,Doron D. Sommer,Jayant Ramakrishna,Stephanie Hoffbauer,Sadaf Arbab-Tafti,Diane Reid,Jonathan MacLean,Gideon Koren +7 more
TL;DR: Ibuprofen in combination with acetaminophen provides safe and effective analgesia in children undergoing tonsillectomy, and post-tonsilllectomy morphine use should be limited, as it may be unsafe in certain children.