L
Leandro A. Barbosa
Researcher at Universidade Federal de São João del-Rei
Publications - 75
Citations - 734
Leandro A. Barbosa is an academic researcher from Universidade Federal de São João del-Rei. The author has contributed to research in topics: Na+/K+-ATPase & Ouabain. The author has an hindex of 15, co-authored 69 publications receiving 572 citations. Previous affiliations of Leandro A. Barbosa include Federal University of Rio de Janeiro.
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Journal ArticleDOI
Iron overload: Effects on cellular biochemistry.
TL;DR: This review will address the biochemical aspects of iron overload at the cellular level and its effects on important cellular structures.
Journal ArticleDOI
21-Benzylidene Digoxin: A Proapoptotic Cardenolide of Cancer Cells That Up-Regulates Na,K-ATPase and Epithelial Tight Junctions
Sayonarah C. Rocha,Marco Túlio C. Pessôa,Luiza D.R. Neves,Silmara L.G. Alves,Luciana Madeira da Silva,Hérica de Lima Santos,Soraya M.F. Oliveira,Alex Gutterres Taranto,Moacyr Comar,Isabella V. Gomes,Fábio Vieira dos Santos,Natasha Paixão,Luis Eduardo M. Quintas,François Noël,Antonio F. Pereira,Ana Claudia Tessis,Natália Lins da Silva Gomes,Otacilio C. Moreira,Ruth Rincon-Heredia,Fernando de Pilla Varotti,Gustavo Blanco,José A.F.P. Villar,Rubén G. Contreras,Leandro A. Barbosa +23 more
TL;DR: Modification of the lactone ring of digoxin provides new properties to the compound, and shows that the structural change introduced could be used for the design of cardiotonic steroid with novel functions.
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Effects of γ-irradiation on the membrane ATPases of human erythrocytes from transfusional blood concentrates
Otacilio C. Moreira,Vanessa H. Oliveira,Luíza B. F. Benedicto,Carmem Martins Nogueira,Julio A. Mignaco,Carlos Frederico Leite Fontes,Leandro A. Barbosa +6 more
TL;DR: Irradiation of blood concentrates increased the plasma membrane permeability to monovalent and divalent cations and would change ion homeostasis and cell function and recommend the use of irradiated blood within a period shorter than 14 days after irradiation.
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Development and Evaluation of Sustained-Release Etoposide-Loaded Poly(ε-Caprolactone) Implants
Ana Gabriela Reis Solano,Ana Gabriela Reis Solano,Adriana de Fátima Pereira,Flávia Carmo Horta Pinto,Letícia Gonçalves Resende Ferreira,Leandro A. Barbosa,Sílvia Ligório Fialho,Patrícia Santiago de Oliveira Patrício,Armando da Silva Cunha,Gisele Rodrigues Da Silva,Gerson Antônio Pianetti +10 more
TL;DR: Poly(ε-caprolactone) implants containing etoposide, an important chemotherapeutic agent and topoisomerase II inhibitor, were fabricated by a melt method and characterized in terms of content uniformity, morphology, drug physical state, and sterility, and good correlation between in vitro and in vivo drug release was found.
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Bioethics and nutrition in adult patients with cancer in palliative care
TL;DR: A nutritionist must consider the individual patient's needs, preferences, and eating habits, which are essential both for controlling symptoms and assuring satisfaction and comfort in palliative care.