L
Lee D.K. Buttery
Researcher at University of Nottingham
Publications - 99
Citations - 9445
Lee D.K. Buttery is an academic researcher from University of Nottingham. The author has contributed to research in topics: Nitric oxide synthase & Stem cell. The author has an hindex of 42, co-authored 97 publications receiving 8955 citations. Previous affiliations of Lee D.K. Buttery include Imperial College London & The Royal Marsden NHS Foundation Trust.
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Gene-expression profiling of human osteoblasts following treatment with the ionic products of Bioglass 45S5 dissolution.
TL;DR: The identification of differentially expressed genes by cDNA microarray analysis has offered new insights into the mode of action of bioactive glasses and has proven to be an effective tool in evaluating their osteoproductive properties.
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Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.
TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
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Bioglass 45S5 stimulates osteoblast turnover and enhances bone formation In vitro: implications and applications for bone tissue engineering.
TL;DR: This study shows that Bioglass 45S5 has the ability to stimulate the growth and osteogenic differentiation of human primary osteoblasts and has potential applications for tissue engineering where this bioactive glass substrate could be used as a template for the formation of bioengineered bone tissue.
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Differentiation of Osteoblasts and in Vitro Bone Formation from Murine Embryonic Stem Cells
Lee D.K. Buttery,S. Bourne,J. D. Xynos,Heather Wood,F.J. Hughes,S. P. F. Hughes,Vasso Episkopou,Julia M. Polak +7 more
TL;DR: The application of a quantitative assay for the derivation of osteoblast lineage progenitors from pluripotent ES cells is demonstrated, which could be applied to obtain purified osteoblasts to analyze mechanisms of osteogenesis and for use of ES cells in skeletal tissue repair.
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Tissue engineering: strategies, stem cells and scaffolds
TL;DR: This review focuses on the developments in custom scaffold design and manufacture, highlighting laser sintering, supercritical carbon dioxide processing, growth factor incorporation and zoning, plasma modification of scaffold surfaces, and novel multi‐use temperature‐sensitive injectable materials.