J
Julia M. Polak
Researcher at Imperial College London
Publications - 169
Citations - 18828
Julia M. Polak is an academic researcher from Imperial College London. The author has contributed to research in topics: Embryonic stem cell & Embryoid body. The author has an hindex of 73, co-authored 169 publications receiving 18081 citations. Previous affiliations of Julia M. Polak include University of Parma & St George's Hospital.
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Journal ArticleDOI
Third-generation Biomedical Materials
Larry L. Hench,Julia M. Polak +1 more
TL;DR: The next generation of biomaterials is combining these two properties, with the aim of developing materials that, once implanted, will help the body heal itself.
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Gene-expression profiling of human osteoblasts following treatment with the ionic products of Bioglass 45S5 dissolution.
TL;DR: The identification of differentially expressed genes by cDNA microarray analysis has offered new insights into the mode of action of bioactive glasses and has proven to be an effective tool in evaluating their osteoproductive properties.
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Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.
TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
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Bioglass 45S5 stimulates osteoblast turnover and enhances bone formation In vitro: implications and applications for bone tissue engineering.
TL;DR: This study shows that Bioglass 45S5 has the ability to stimulate the growth and osteogenic differentiation of human primary osteoblasts and has potential applications for tissue engineering where this bioactive glass substrate could be used as a template for the formation of bioengineered bone tissue.
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Expression of angiogenesis‐related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis
Rubin M. Tuder,Mati Chacon,Lori Alger,Jun Wang,Laimute Taraseviciene-Stewart,Yasunori Kasahara,Carlyne D. Cool,Anne E. Bishop,Mark W. Geraci,Gregg L. Semenza,Magdi H. Yacoub,Julia M. Polak,Norbert F. Voelkel +12 more
TL;DR: It is postulated that in lungs with SPH, endothelial cells in plexiform lesions express genes encoding for proteins involved in angiogenesis, in particular, vascular endothelial growth factor (VEGF) and those involved in VEGF receptor‐2 (VEGFR‐2) signalling.