Leena Sharma

TL;DR: This article is part 1 of a two-part summary of an NIH conference, Stepping Away with OA: Prevention of Onset, Progression, and Disability of Osteoarthritis, which brought together experts in osteoarth arthritis from diverse backgrounds and provided a multidisciplinary and comprehensive summary of recent advances in the prevention.

TL;DR: This is the first demonstration that in primary knee OA varus alignment increases risk of medial OA progression, that valgus alignment increased risk of lateral OA progress, that burden of malalignment predicts decline in physical function, and that these effects can be detected after as little as 18 months of observation.

TL;DR: There is a wide range of leg symptoms in persons with PAD beyond that of classic IC, and functional impairments are found in every PAD symptom group, and the degree of functional limitation varies depending on the type of leg symptom.

TL;DR: There is a significant relationship between the adduction moment and OA disease severity and serum hyaluronan levels correlate with joint space width but not with theAdduction moment.

TL;DR: Factors placing individuals with knee OA at greater risk of a poor function outcome by at least 1 of the 2 function measures included the local factors laxity and proprioceptive inaccuracy, as well as age, BMI, and knee pain intensity.