L
Lei Huang
Researcher at Anhui Medical University
Publications - 66
Citations - 2393
Lei Huang is an academic researcher from Anhui Medical University. The author has contributed to research in topics: Cancer & Population. The author has an hindex of 20, co-authored 62 publications receiving 1653 citations. Previous affiliations of Lei Huang include German Cancer Research Center & Southern Medical University.
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Journal ArticleDOI
Rapid asymptomatic transmission of COVID-19 during the incubation period demonstrating strong infectivity in a cluster of youngsters aged 16-23 years outside Wuhan and characteristics of young patients with COVID-19: A prospective contact-tracing study.
Lei Huang,Xiuwen Zhang,Xinyue Zhang,Zhijian Wei,Lingli Zhang,Jingjing Xu,Peipei Liang,Yuanhong Xu,Chengyuan Zhang,A-Man Xu +9 more
TL;DR: SARS-CoV-2-infection presented strong infectivity during the incubation-period with rapid transmission in this cluster of youngsters outside Wuhan, China, and COVID-19 developed in these youngsters had fast onset and various nonspecific atypical manifestations, and were much milder than in older patients as previously reported.
Journal ArticleDOI
CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts
Chun-Mei Tang,Ming Zhang,Lei Huang,Zhi-Qin Hu,Zhi-Qin Hu,Zhi-Qin Hu,Jie-Ning Zhu,Jie-Ning Zhu,Zhen Xiao,Zhuo Zhang,Qiu-Xiong Lin,Qiu-Xiong Lin,Xi-Long Zheng,Min Yang,Min Yang,Shulin Wu,Shulin Wu,Jianding Cheng,Zhi-Xin Shan,Zhi-Xin Shan +19 more
TL;DR: Results reveal that suppressing the function of miR-26b-5p contributes to the pro-fibrosis effect of circRNA_000203 in cardiac fibroblasts.
Journal Article
Epithelial-mesenchymal transition in gastric cancer.
Lei Huang,Ruo-Lin Wu,A-Man Xu +2 more
TL;DR: Investigating potential mechanisms modulating GC cell EMT and discovering novel EMT regulators will further elucidate GC biology, and may provide new biomarkers for early GC detection and potentially efficient targets for preventative and curative anti-GC intervention approaches to prevent local and distant invasions.
Journal ArticleDOI
Resection of pancreatic cancer in Europe and USA: An international large-scale study highlighting large variations
Lei Huang,Lina Jansen,Yesilda Balavarca,Esther Molina-Montes,Masoud Babaei,Lydia G. M. van der Geest,Valery E.P.P. Lemmens,Liesbet Van Eycken,Harlinde De Schutter,T.B. Johannesen,Claus Cw Fristrup,Michael Bau Mortensen,Maja Primic-Žakelj,Vesna Zadnik,Nikolaus Becker,Thilo Hackert,Margit Mägi,Tiziana Cassetti,Romano Sassatelli,Robert Grützmann,Susanne Merkel,Ana Filipa Gonçalves,Maria José Bento,Péter Hegyi,Gábor Lakatos,Andrea Szentesi,Michel Moreau,Tony van de Velde,Annegien Broeks,Milena Sant,Pamela Minicozzi,Vincenzo Mazzaferro,Francisco X. Real,Alfredo Carrato,Xavier Molero,Marc G. Besselink,Núria Malats,Markus W. Büchler,Petra Schrotz-King,Hermann Brenner +39 more
TL;DR: Investigation of variations in resection for PaC in Europe and USA and determinants for its utilisation found rates of PaC resection remain low in European and USA with great international variations.
Journal ArticleDOI
Interleukin-17–Producing Neutrophils Link Inflammatory Stimuli to Disease Progression by Promoting Angiogenesis in Gastric Cancer
Tuanjie Li,Yuming Jiang,Yanfeng Hu,Lei Huang,Jiang Yu,Liying Zhao,Haijun Deng,Tingyu Mou,Hao Liu,Yang Yang,Qi Zhang,Guoxin Li +11 more
TL;DR: Data provide direct evidence supporting the pivotal role of neutrophils in gastric cancer progression and reveal a novel immune escape mechanism involving fine-tuned collaborative action between cancer cells and immune cells in the distinct tumor microenvironment.