Leijie Zhou

TL;DR: Under mild conditions, palladium-catalyzed asymmetric tandem reaction of various substituted VECs and coumalates or pyrones proceeds smoothly to produce the corresponding medium-sized heterocyclic compounds in high yields with very high enantioselectivities.

TL;DR: In this paper, a formal cycloaddition of zwitterionic allylpalladium intermediates with 1,3-dipoles was developed, providing N,O-containing eight-membered heterocyclic compounds in high yields.

TL;DR: The first catalytic enantioselective [4 + 3] annulation of allenoates with C,N-cyclic azomethine imines is developed, which works efficiently under mild reaction conditions to afford seven-membered ring-fused quinazoline-based tricyclic heterocycles in high yields with good to excellent diastereo- and enantiOSElectivities.

TL;DR: Phosphine-catalyzed [2 + 4] annulation of allenoates with thiazolone-derived alkenes has been achieved under mild conditions, giving biologically important 6,7-dihydro-5H-pyrano[2,3-d]thiazole derivatives in high to excellent yields.

TL;DR: This reaction represents the first Pd-catalyzed asymmetric decarboxylative cycloaddition of vinyl benzoxazinones with imines, affording the tetrahydroquinazolines bearing several functional rings in high yields with good to excellent diastereoselectivities and excellent enantioselectivity.