L
Leila Cochon
Researcher at State University of Campinas
Publications - 43
Citations - 1631
Leila Cochon is an academic researcher from State University of Campinas. The author has contributed to research in topics: Population & Levonorgestrel. The author has an hindex of 18, co-authored 40 publications receiving 1250 citations.
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Journal ArticleDOI
Neutralizing antibodies against the SARS-CoV-2 Delta and Omicron variants following heterologous CoronaVac plus BNT162b2 booster vaccination
Eddy Perez-Then,Carolina Lucas,V. Monteiro,Marija Miric,Vivian Brache,Leila Cochon,Chantal B.F. Vogels,Amyn A. Malik,Elena De la Cruz,Aidelis Jorge,Margarita De Los Santos,Patricia Leon,Mallery I. Breban,K. Billig,Inci Yildirim,Claire Pearson,Randy Downing,Emily Gagnon,Anthony Muyombwe,Jafar Razeq,Melissa Campbell,Albert I. Ko,Saad B. Omer,Nathan D. Grubaugh,Sten H. Vermund,Akiko Iwasaki +25 more
TL;DR: In this paper , the authors evaluated the effects of a heterologous BNT162b2 mRNA vaccine booster on the humoral immunity of participants who had received a two-dose regimen of CoronaVac, an inactivated vaccine used globally.
Journal ArticleDOI
Pituitary-ovarian function following the standard levonorgestrel emergency contraceptive dose or a single 0.75-mg dose given on the days preceding ovulation.
Horacio B. Croxatto,Vivian Brache,Margarita Pavez,Leila Cochon,M. L. Forcelledo,F. Alvarez,Rebeca Massai,Anibal Faundes,A.M. Salvatierra +8 more
TL;DR: In conclusion, LNG can disrupt the ovulatory process in 93% of cycles treated when the diameter of the dominant follicle is between 12 and 17 mm, and the present data suggest that half the dose may be as effective as the standard dose.
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Immediate pre-ovulatory administration of 30 mg ulipristal acetate significantly delays follicular rupture
Vivian Brache,Leila Cochon,C. Jesam,R. Maldonado,A.M. Salvatierra,D. P. Levy,E. Gainer,Horacio B. Croxatto +7 more
TL;DR: It is demonstrated that UPA can significantly delay follicular rupture when given immediately before ovulation, which could possibly prevent pregnancy when administered in the advanced follicular phase, even if LH levels have already begun to rise, a time when levonorgestrel EC is no longer effective in inhibiting ovulation.
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Nonmenstrual adverse events during use of implantable contraceptives for women: data from clinical trials.
TL;DR: The vast experience reported in the clinical studies reviewed here show that all existing implantable contraceptives are equally safe and can probably be attributed to the low-hormonal dose delivered by progestin-implant systems.
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Ulipristal acetate prevents ovulation more effectively than levonorgestrel: analysis of pooled data from three randomized trials of emergency contraception regimens.
TL;DR: Although no EC treatment is 100% effective in inhibiting follicular rupture when administered in the late follicular phase, UPA is the most effective treatment, delaying ovulation for at least 5 days in 59% of the cycles.