L
Leslie M. Loew
Researcher at University of Connecticut
Publications - 288
Citations - 19918
Leslie M. Loew is an academic researcher from University of Connecticut. The author has contributed to research in topics: Membrane & Membrane potential. The author has an hindex of 68, co-authored 276 publications receiving 18813 citations. Previous affiliations of Leslie M. Loew include Cornell University & University of Connecticut Health Center.
Papers
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Journal ArticleDOI
Correction: Stoichiometry of Nck-dependent actin polymerization in living cells.
Jonathon A. Ditlev,Paul J. Michalski,Greg Huber,Gonzalo M. Rivera,William A. Mohler,Leslie M. Loew,Bruce J. Mayer +6 more
TL;DR: One of the expression constructs used in this publication, which was obtained as a gift from another laboratory, was incorrect and what was described as a fusion of GFP with full-length N-WASp was wrong.
Patent
Compounds and methods for optical sensing of electrical activity in biological systems
TL;DR: In this article, tethered chromophore compositions comprising a membrane-spanning tether are described, useful for measuring action potentials and other fast electrical events in cells and tissues.
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Noise regulation by heterotypic biomolecular condensates
TL;DR: In this article , the authors extended the buffering framework to multicomponent (heterotypic) systems where a solubility product of concentrations in the dilute phase maintains an approximately constant level (Ksp) above the phase separation threshold.
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Near infrared voltage sensitive dyes based on chromene electron donors.
Ping Yan,Valentina Biasci,G. H. B. Judge,Corey D. Acker,Alex L. Monroe,Leonardo Sacconi,Leslie M. Loew +6 more
TL;DR: In this paper , it was shown that replacing naphthalene with chromene induces a 60-80 nm red-shift in the absorption and emission spectra while maintaining the structure at the same size and fluorescence quantum yield at a same level.
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The maximum solubility product marks the threshold for condensation of multivalent biomolecules
TL;DR: In this paper , the authors explored the limits of the solubility product (SP) concept using spatial Langevin dynamics and rule-based stochastic simulations and revealed the importance of intracluster binding in steering the free and cluster phase molecular distributions.