Leticia Olvera

TL;DR: RegulonDB is the primary reference database of the best-known regulatory network of any free-living organism, that of Escherichia coli K-12, and has summaries for every transcription factor and TF-binding sites with internal symmetry.

TL;DR: The new information in RegulonDB, now with more than 2400 experimentally determined TSSs, strengthens the accuracy of promoter prediction, operon structure, and regulatory networks and provides valuable new information that will facilitate the understanding from a global perspective the complex and intricate regulatory network that operates in E. coli.

TL;DR: The results demonstrate the ability of the computational approach to predict specific functions without taking into account sequence similarity, and the approach, applied to the thiamin biosynthesis pathway, predicts seven instances in which known enzymes have been displaced by analogous proteins.

TL;DR: This work analyzed the transcriptional organization of the CRISPR/Cas system as well as the positive and negative regulators involved in its genetic expression in Salmonella enterica serovar Typhi and provided evidence that there are multiple modulators involved in the genetic expression of this immune system in S. Typhi IMSS-1.

TL;DR: It is reported that the expression of pilA, which encodes the pilistructural protein, is directly regulated by a two-component regulatory system in which PilR functions as an RpoN-dependent enhancer binding protein.