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Barbara A. Methé

Researcher at J. Craig Venter Institute

Publications -  63
Citations -  14045

Barbara A. Methé is an academic researcher from J. Craig Venter Institute. The author has contributed to research in topics: Genome & Geobacter sulfurreducens. The author has an hindex of 34, co-authored 63 publications receiving 12627 citations. Previous affiliations of Barbara A. Methé include University of Massachusetts Amherst.

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Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons

TL;DR: A new chimera detection tool called Chimera Slayer (CS), which detects chimeras with greater sensitivity than previous methods, performs well on short sequences such as those produced by the 454 Life Sciences (Roche) Genome Sequencer, and can scale to large data sets.
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Antibiotics in early life alter the murine colonic microbiome and adiposity

TL;DR: A model of adiposity is generated by giving subtherapeutic antibiotic therapy to young mice and changes in the composition and capabilities of the gut microbiome are evaluated, demonstrating the alteration of early-life murine metabolic homeostasis through antibiotic manipulation.
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The minimum information about a genome sequence (MIGS) specification.

Dawn Field, +71 more
- 01 May 2008 - 
TL;DR: Here, the minimum information about a genome sequence (MIGS) specification is introduced with the intent of promoting participation in its development and discussing the resources that will be required to develop improved mechanisms of metadata capture and exchange.
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Genome of Geobacter sulfurreducens: Metal Reduction in Subsurface Environments

TL;DR: The complete genome sequence of Geobacter sulfurreducens, a δ-proteobacterium, reveals unsuspected capabilities, including evidence of aerobic metabolism, one-carbon and complex carbon metabolism, motility, and chemotactic behavior, which suggest the organism has the potential for use in bioremediation of radioactive metals and in the generation of electricity.