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Barbara A. Methé
Researcher at J. Craig Venter Institute
Publications - 63
Citations - 14045
Barbara A. Methé is an academic researcher from J. Craig Venter Institute. The author has contributed to research in topics: Genome & Geobacter sulfurreducens. The author has an hindex of 34, co-authored 63 publications receiving 12627 citations. Previous affiliations of Barbara A. Methé include University of Massachusetts Amherst.
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Journal ArticleDOI
Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons
Brian J. Haas,Dirk Gevers,Ashlee M. Earl,Mike Feldgarden,Doyle V. Ward,Georgia Giannoukos,Dawn Ciulla,Diana Tabbaa,Sarah K. Highlander,Erica Sodergren,Barbara A. Methé,Todd Z. DeSantis,Joseph F. Petrosino,Rob Knight,Bruce W. Birren +14 more
TL;DR: A new chimera detection tool called Chimera Slayer (CS), which detects chimeras with greater sensitivity than previous methods, performs well on short sequences such as those produced by the 454 Life Sciences (Roche) Genome Sequencer, and can scale to large data sets.
Journal ArticleDOI
Antibiotics in early life alter the murine colonic microbiome and adiposity
Ilseung Cho,Shingo Yamanishi,Laura M. Cox,Barbara A. Methé,Jiri Zavadil,Kelvin Li,Zhan Gao,Douglas Mahana,Kartik Raju,Isabel Teitler,Huilin Li,Alexander V. Alekseyenko,Martin J. Blaser +12 more
TL;DR: A model of adiposity is generated by giving subtherapeutic antibiotic therapy to young mice and changes in the composition and capabilities of the gut microbiome are evaluated, demonstrating the alteration of early-life murine metabolic homeostasis through antibiotic manipulation.
Journal ArticleDOI
The minimum information about a genome sequence (MIGS) specification.
Dawn Field,George M. Garrity,Tanya Gray,Norman Morrison,Jeremy D. Selengut,Peter Sterk,Tatiana Tatusova,Nicholas R. Thomson,Michael J. Allen,Samuel V. Angiuoli,Michael Ashburner,Nelson Axelrod,Sandra L. Baldauf,S. Ballard,Jeffrey L. Boore,Guy Cochrane,James R. Cole,Peter Dawyndt,Paul De Vos,Claude W. dePamphilis,Robert Edwards,Nadeem Faruque,Robert G. Feldman,Jack A. Gilbert,Paul Gilna,Frank Oliver Glöckner,Philip Goldstein,Robert P. Guralnick,Daniel H. Haft,David Hancock,Henning Hermjakob,Christiane Hertz-Fowler,Phil Hugenholtz,Ian Joint,Leonid Kagan,Matthew D. Kane,Jessie Kennedy,George A. Kowalchuk,Renzo Kottmann,Eugene Kolker,Saul A. Kravitz,Nikos C. Kyrpides,Jim Leebens-Mack,Suzanna E. Lewis,Kelvin Li,Allyson L. Lister,Phillip Lord,Natalia Maltsev,Victor Markowitz,Jennifer B. H. Martiny,Barbara A. Methé,Ilene Mizrachi,Richard Moxon,Karen E. Nelson,Julian Parkhill,Lita M. Proctor,Owen White,Susanna-Assunta Sansone,Andrew J. Spiers,Robert Stevens,Paul Swift,Chris F. Taylor,Yoshio Tateno,Adrian Tett,Sarah L. Turner,David W. Ussery,Bob Vaughan,Naomi L. Ward,Trish Whetzel,Ingio San Gil,Gareth A. Wilson,Anil Wipat +71 more
TL;DR: Here, the minimum information about a genome sequence (MIGS) specification is introduced with the intent of promoting participation in its development and discussing the resources that will be required to develop improved mechanisms of metadata capture and exchange.
Journal ArticleDOI
Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis.
John F. Heidelberg,Ian T. Paulsen,Karen E. Nelson,Eric Gaidos,Eric Gaidos,William C. Nelson,Timothy D. Read,Jonathan A. Eisen,Rekha Seshadri,Naomi L. Ward,Barbara A. Methé,Rebecca A. Clayton,Terry E. Meyer,A. I. Tsapin,James Scott,Maureen J. Beanan,Lauren M. Brinkac,Sean C. Daugherty,Robert T. DeBoy,Robert J. Dodson,A. Scott Durkin,Daniel H. Haft,James F. Kolonay,Ramana Madupu,Jeremy Peterson,Lowell Umayam,Owen White,Alex M. Wolf,Jessica Vamathevan,Janice Weidman,Marjorie Impraim,K. Lee,Kristy Berry,Chris Lee,Jacob L. Mueller,Hoda Khouri,John Gill,T. Utterback,Lisa McDonald,Tamara Feldblyum,Hamilton O. Smith,J. Craig Venter,Kenneth H. Nealson,Kenneth H. Nealson,Claire M. Fraser +44 more
TL;DR: This genome sequence represents a critical step in the elucidation of the pathways for reduction (and bioremediation) of pollutants such as uranium (U) and chromium (Cr), and offers a starting point for defining this organism's complex electron transport systems and metal ion–reducing capabilities.
Journal ArticleDOI
Genome of Geobacter sulfurreducens: Metal Reduction in Subsurface Environments
Barbara A. Methé,Karen E. Nelson,Jonathan A. Eisen,Ian T. Paulsen,William C. Nelson,John F. Heidelberg,Dongying Wu,Martin Wu,Naomi L. Ward,Maureen J. Beanan,Robert J. Dodson,R. Madupu,Lauren M. Brinkac,Sean C. Daugherty,Robert T. DeBoy,Anthony S. Durkin,Michelle L. Gwinn,James F. Kolonay,Steven A. Sullivan,Daniel H. Haft,Jeremy D. Selengut,Tanja M. Davidsen,Nikhat Zafar,Owen White,Bao Tran,Claudia M. Romero,Heather Forberger,J. Weidman,H. Khouri,Tamara Feldblyum,T. Utterback,S. van Aken,Derek R. Lovley,Claire M. Fraser +33 more
TL;DR: The complete genome sequence of Geobacter sulfurreducens, a δ-proteobacterium, reveals unsuspected capabilities, including evidence of aerobic metabolism, one-carbon and complex carbon metabolism, motility, and chemotactic behavior, which suggest the organism has the potential for use in bioremediation of radioactive metals and in the generation of electricity.