L
Lewis K. Schrager
Researcher at National Institutes of Health
Publications - 21
Citations - 2998
Lewis K. Schrager is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Acquired immunodeficiency syndrome (AIDS) & Multicenter AIDS Cohort Study. The author has an hindex of 18, co-authored 21 publications receiving 2970 citations. Previous affiliations of Lewis K. Schrager include Yeshiva University & Northwestern University.
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Journal ArticleDOI
Studies in subjects with long-term nonprogressive human immunodeficiency virus infection.
Giuseppe Pantaleo,Stefano Menzo,Mauro Vaccarezza,Cecilia Graziosi,Oren J. Cohen,James F. Demarest,David C. Montefiori,Jan M. Orenstein,Cecil H. Fox,Lewis K. Schrager,Joseph B. Margolick,Susan Buchbinder,Janis V. Giorgi,Anthony S. Fauci +13 more
TL;DR: In persons who remain free of disease for many years despite HIV infection the viral load is low, but viral replication persists, and lymph-node architecture and immune function appear to remain intact.
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Effectiveness of Potent Antiretroviral Therapy on Time to AIDS and Death in Men With Known HIV Infection Duration
Roger Detels,Alvaro Muñoz,Glen McFarlane,Lawrence A. Kingsley,Joseph B. Margolick,Janis V. Giorgi,Lewis K. Schrager,John P. Phair +7 more
TL;DR: In the calendar period when potent antiretroviral therapy was introduced, the time to development of AIDS and time to death were extended, and rate of CD4 cell count decline was arrested.
Journal ArticleDOI
Depressive Symptoms as Predictors of Medical Outcomes in HIV Infection
Constantine G. Lyketsos,Donald R. Hoover,Marcella Guccione,Walton Senterfitt,Mary Amanda Dew,Jerry Wesch,Mark J. VanRaden,Glenn J. Treisman,Hal Morgenstern,A. J. Saah,John Palenicek,H. Armenian,H. Farzadegan,Neil M.H. Graham,Joseph B. Margolick,Julie H. McArthur,John P. Phair,Joan S. Chmiel,Bruce A. Cohen,Maurice R.G. O'Gorman,D. Variakojis,J. Wesch,Steven M. Wolinsky,Roger Detels,Barbara R. Visscher,I. S. Y. Chen,Dudley Jp,J. L. Fahey,Janis V. Giorgi,M. Lee,O. Martinez-Mara,Eric N. Miller,Parunag Nishanian,Jeremy M. G. Taylor,J. Zack,C. R. Rinaldor,L. A. Kingsley,James T. Becker,P. Gupta,M. Ho,Alvaro Muñoz,Lisa P. Jacobson,T. Beaty,Noya Galai,Leon G. Epstein,M. Guccione,D. R. Hoover,C. Meinert,Kenrad E. Nelson,S. Piantadosi,S. Su,Lewis K. Schrager,Sten H. Vermund,Richard A. Kaslow,M. J. VanRaden,D. Seminara +55 more
TL;DR: There is no evidence that depressive symptoms independently prognosticate worse outcomes in HIV infection, and future studies of the relationship between depression and HIV outcome should consider these variables as confounders.
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Acquired immune deficiency syndrome occurring within 5 years of infection with human immunodeficiency virus type-1: the Multicenter AIDS Cohort Study.
John P. Phair,Lisa P. Jacobson,Roger Detels,C. R. Rinaldo,A. J. Saah,Lewis K. Schrager,Alvaro Muñoz +6 more
TL;DR: It is suggested that sexually transmitted co-factors, preseroconversion and/or postseroconversion, play a role in the progression of HIV-1 infection and greater sexual activity could increase the hazard of exposure to a more virulent HIV- 1 strain.
Journal ArticleDOI
Trends in the Incidence of Outcomes Defining Acquired Immunodeficiency Syndrome (AIDS) in the Multicenter AIDS Cohort Study: 1985–1991
Alvaro Muñoz,Lewis K. Schrager,Lewis K. Schrager,Helena Bacellar,Helena Bacellar,Ilene S. Speizer,Sten H. Vermund,Sten H. Vermund,Roger Detels,Roger Detels,Alfred J. Saah,Alfred J. Saah,L. A. Kingsley,L. A. Kingsley,Daniela Seminara,Daniela Seminara,John P. Phair,John P. Phair +17 more
TL;DR: The trend observed in the incidence of other opportunistic infections underscores the need for developing and testing new strategies to curtail or delay the onset of these diseases.