L
Lian Hui Zhu
Researcher at Chinese Academy of Sciences
Publications - 1
Citations - 221
Lian Hui Zhu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: RIG-I & HECT domain. The author has an hindex of 1, co-authored 1 publications receiving 195 citations.
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Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification.
TL;DR: HECT domain and RLD 5 is identified as a specific binding protein of IRF3 by immunoprecipitation and characterizes HERC5 as a positive regulator of innate antiviral responses, which sustainsIRF3 activation via a novel posttranslational modification, ISGylation.