L
Liang Xiao
Researcher at University of Southern California
Publications - 11
Citations - 478
Liang Xiao is an academic researcher from University of Southern California. The author has contributed to research in topics: Dendritic cell & Immune system. The author has an hindex of 9, co-authored 11 publications receiving 413 citations.
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Journal ArticleDOI
Crosslinked multilamellar liposomes for controlled delivery of anticancer drugs.
Kye-Il Joo,Liang Xiao,Shuanglong Liu,Yarong Liu,Chi-Lin Lee,Peter S. Conti,Michael K. Wong,Zibo Li,Pin Wang +8 more
TL;DR: In vivo experiments showed that the CML-Dox formulation reduced systemic toxicity and significantly improved therapeutic activity in inhibiting tumor growth compared to that of UL-D Crosslinked multilamellar liposome or DLL-D ox.
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Enhanced Real-Time Monitoring of Adeno-Associated Virus Trafficking by Virus-Quantum Dot Conjugates
TL;DR: The findings reveal the potential of this QD-labeling method for monitoring the intracellular dynamics of virus-host cell interactions and interrogating the molecular mechanisms of viral infection in greater detail.
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A potent immunotoxin targeting fibroblast activation protein for treatment of breast cancer in mice.
Jinxu Fang,Liang Xiao,Kye-Il Joo,Yarong Liu,Chupei Zhang,Shuanglong Liu,Peter S. Conti,Zibo Li,Pin Wang +8 more
TL;DR: A novel immune‐based approach to specifically deplete FAP‐expressing TAFs in a mouse 4T1 metastatic breast cancer model is evaluated and the potential use of immunotoxin αFAP‐PE38 is highlighted to provide a rationale for the use of this Immunotoxin in cancer therapy.
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In situ modulation of dendritic cells by injectable thermosensitive hydrogels for cancer vaccines in mice.
TL;DR: It is demonstrated that GM-CSF-releasing mPEG–PLGA hydrogels successfully recruit and house DCs and macrophages, allowing the subsequent introduction of antigens by vectors to activate the resident cells, thus, initiating antigen presentation and triggering immune response.
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PD-1/PD-L1 blockade can enhance HIV-1 Gag-specific T cell immunity elicited by dendritic cell-directed lentiviral vaccines.
TL;DR: These studies offer evidence to support the use of PD-1/PD-L1 blockade as an adjuvant modality to enhance antigen-specific immune responses elicited by T cell-based immunizations such as DCLV.