L
Librado Carrasco
Researcher at University of Córdoba (Spain)
Publications - 168
Citations - 3500
Librado Carrasco is an academic researcher from University of Córdoba (Spain). The author has contributed to research in topics: Virus & African swine fever virus. The author has an hindex of 31, co-authored 164 publications receiving 3113 citations. Previous affiliations of Librado Carrasco include Cordoba University.
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Journal ArticleDOI
An update on the epidemiology and pathology of African swine fever.
TL;DR: This review addresses each of the main characteristics of this infection, including its current distribution and routes of transmission, and aims to update knowledge of the disease in order to improve early detection of ASF in the field and allow implementation of public health programmes.
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Pathology of African swine fever: the role of monocyte-macrophage.
TL;DR: Proinflammatory activation is the initial cause of clinical and lesional pictures in ASF, including fever and changes in levels of acute phase proteins, and levels of IFN-β and -γ are increased from initial phase of acute ASF.
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Cytokine Expression by Macrophages in the Lung of Pigs Infected with the Porcine Reproductive and Respiratory Syndrome Virus
Jaime Gómez-Laguna,Francisco J. Salguero,I. Barranco,F.J. Pallarés,Irene M. Rodríguez-Gómez,Antonio Bernabé,Librado Carrasco +6 more
TL;DR: It is suggested that PRRSV modulates the immune response by the up-regulation of IL-10, which may in turn reduce expression of cytokines involved in viral clearance (e.g.IFN-α, IFN-γ, IL-12p40 and TNF-α).
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Experimental African swine fever: apoptosis of lymphocytes and virus replication in other cells
José C. Gómez-Villamandos,José Hervás,Aniceto Méndez,Librado Carrasco,Juana Martín de las Mulas,Carlos J. Villeda,P. J. Wilkinson,M. A. Sierra +7 more
TL;DR: The results suggest that mononuclear phagocyte system (MPS) cell activation, and the resulting release of cytokines, could induce apoptosis of lymphocytes and virus replication in non-MPS cells.
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Immunopathogenesis of porcine reproductive and respiratory syndrome in the respiratory tract of pigs
TL;DR: With the emergence of highly pathogenic PRRSV, there is a need for more information on the immunopathogenesis of different strains of PRRS, particularly to develop more effective vaccines.