Showing papers in "Journal of Comparative Pathology in 2015"

TL;DR: This review addresses each of the main characteristics of this infection, including its current distribution and routes of transmission, and aims to update knowledge of the disease in order to improve early detection of ASF in the field and allow implementation of public health programmes.

TL;DR: It is concluded that, while the nasal cavity of the monkey might be more similar to that of man, each laboratory animal species provides a model that responds in a characteristic and species-specific manner, and careful consideration must be given to the anatomical differences between a given animal model and man.

TL;DR: A retrospective study of tumours in cats in Switzerland from 1965 to 2008 finds that several breeds had significantly lower odds ratios for developing a tumour compared with European shorthair cats and female cats had higher risk of developing a cancer compared with male cats.

TL;DR: Phylogenetic analysis of the nucleotide sequences obtained from PCR products indicated that the HEV strains present in wild boars and the human population all belonged to genotype 3, supporting the zoonotic role of wild boar in the spread of HEV infection.

TL;DR: Examination of the expression of the pro-inflammatory cytokines interleukin (IL)-1α, IL-6 and tumour necrosis factor (TNF)-α in ovarian cells from cows with cystic ovarian disease (COD) as compared with that in ovarian structures from regularly cycling cows found them to be related to ovulation failure and development of follicular cysts.

TL;DR: In experimentally infected cattle, pulmonary granulomas of all stages were examined 150 days after aerosol exposure to M. bovis, and relative expression of the various cytokines was characteristic of a Th1 response, with high TNF-α and IFN-γ expression and low IL-10 expression.

TL;DR: It is demonstrated that canine STSs display histological and immunohistochemical features similar to their human equivalents, a particular opportunity exists to understand the biology and treatment of human STS by potentially including dogs as clinical models.

TL;DR: Th1- and Th17-related cytokines appear to play a role in restricting parasite growth via iNOS activation and decrease susceptibility of dogs to CVL.

TL;DR: Comparisons of pathogenicity of single or dual infections with type 1 and type 2 porcine reproductive and respiratory syndrome virus in pigs found significant differences in virulence, viraemia, lung lesion score and virus distribution within lung lesions were not observed.

TL;DR: The majority of lesions were classified as carcinomas with 32 tubular, 16 papillary, 12 tubulopapillary, 11 solid, nine adenosquamous, nine comedo type, five complex, four ductal, three cribriform, three anaplastic and one spindle -cell carcinoma.

TL;DR: This is the first description of disseminated fatal toxoplasmosis in a captive harbour porpoise that lived in an open sea basin and was regarded as the most likely source of infection.

TL;DR: Although the significance of the high incidence of periodontitis and TMJ-OA in the northern fur seal remains unknown, the occurrence and severity of these diseases found in this study may play an important role in this species morbidity and mortality.

TL;DR: An outbreak of tuberculosis among a group of rhesus monkeys living in a closed, long-term colony coincided with reactivation of a TB infection in a co-worker who never had direct access to the animal house or laboratories.

TL;DR: Pythiosis is reported for the first time in a goat that had daily access to an aquatic environment and had developed an ulcerative lesion on the skin of the left hindlimb.

TL;DR: Although the significance of the high incidence of periodontitis and TMJ-OA in the Eastern Pacific harbor seal remains unknown, the occurrence and severity of these diseases as found in this study may play an important role in the morbidity and mortality of this species.

TL;DR: The results of this study provide some evidence in support of the hypothesis that the three CODD-associated Treponema phylogroups are involved in the aetiopathogenesis of this disease.

TL;DR: The findings included supernumerary teeth, absence of teeth, mild class II malocclusion, severe tooth wear, periodontitis, calculus, caries, tooth fractures and the presence of enamel defects.

TL;DR: The TMA platform preserves the molecular profile of canine and feline mammary tumour markers, representing a useful tool for rapid and cost-effective analysis for the first phenotypic screening using OR, PR and c-erbB2 antibodies.

TL;DR: Prototheca zopfii is revealed as an additional Prototheca species associated with feline protothecosis and marked pyogranulomatous inflammation with numerous intralesional algae is described.

TL;DR: A 7-month-old male cross breed dog was presented with hyperextensible skin and atrophic scarring, suggesting that the defective collagen formation extended to the vasculature, and this is the first report of Ehlers-Danlos syndrome with vascular involvement in animals.

TL;DR: Findings indicate that there is a subgroup of poorly differentiated equine CMCTs, in which there is an association between aberrant KIT expression, high proliferative rate and potential aggressive behaviour, all features that confirm at least the poorly differentiated CMCT as a true neoplastic processes.

TL;DR: The cytokines examined likely play a role in pulmonary defence against M. bovis infection and results in expression of a number of cytokines capable of inducing lung lesions and hyperplasia of the BALT.

TL;DR: It is established that there is a robust population of immune cells within canine oligodendrogliomas and indicates that further study is needed to determine the role of these cells in tumour pathogenesis and progression.

TL;DR: In this paper, the onset and distribution of infectivity and disease-specific prion protein (PrP(d)) accumulation was studied in Romney and Suffolk sheep following experimental oral infection with cattle-derived bovine spongiform encephalopathy (BSE) agent.

TL;DR: This report documents fatal systemic neosporosis and enteroepithelial stages of N. caninum in a naturally infected puppy from a dairy cattle farm in Turkey, which is the first definition of intestinal neOSporosis in a Naturally infected dog as well as the first evidence of fatal canine neosportosis in Turkey.

TL;DR: The results support the idea that the lungs have a remarkable overcapacity for oxygen consumption and that the development of pulmonary disease continuously reduces the capacity foroxy consumption.

TL;DR: There is a correlation between high expression of the 27.8 kDa receptor and efficient LCDV propagation and the wide tissue distribution of the receptor might be one reason why LCDV can infect various tissues leading to systemic infection.

TL;DR: The pathological findings observed in the cow and her fetus, together with the presence of OvHV-2 DNA in tissues of these animals, are suggestive of transplacental transmission of OvVirus 2 in SA-MCF in cattle.

TL;DR: Investigation of E-cadherin expression and its relationship to transcriptional repressors in the progression from carcinoma 'in situ' to invasion to lymph node metastasis in spontaneously arising canine invasive micropapillary carcinoma (IMPC) finds that canine mammary IMPCs had a loss ofE-c cadherin from carcinomas in situ to invasive areas, which appears to be induced by the transcription factor SNAIL.

TL;DR: This study reports the construction of a comprehensive gene regulatory network (GRN) for canine diffuse large B-cell lymphoma (DLBCL), the most common type of canine lymphoma, and performs analysis for detection of major functional modules and hub genes (the most important genes in a GRN).