Showing papers by "Lin Jiang published in 2007"
TL;DR: This paper describes the use of the developed co-simulation environment for a high-speed merchant vessel propulsion system application and provides an integrated suite of tools to support all the development life-cycle of the system.
23 citations
03 May 2007
TL;DR: In this article, a robust adaptive control of induction motor based on input-output linearization and perturbation estimation is proposed, which can guarantee bounded track errors for bounded time-varying perturbations and achieve asymptotic track when the uncertain parameters converge to unknown constants.
Abstract: This paper investigates a novel robust adaptive control of induction motor based on input-output linearization and perturbation estimation. After representing induction motor as two interconnected subsystems, the lumped term of all nonlinearities, uncertainties and interaction between subsystems are defined as system perturbations and estimated by high-gain perturbation observer. The estimates are employed to achieve the decoupling and robust adaptive linearizing control of flux/speed dynamics. The proposed control can deal with time-varying uncertainties and doesn't require the detailed model of the induction motor. It can guarantee bounded track errors for bounded time-varying perturbations and achieve asymptotical track when the uncertain parameters converge to unknown constants. The performance of the proposed controller is verified by simulation studies.
3 citations
TL;DR: RNAi inhibits the expression of heparanase and the invasion ability of human gastric cancer cells, suggesting that Heparanase may be a new target in treatment of Gastric cancer's metastasis.
Abstract: OBJECTIVE: To investigate the inhibitory effect of siRNA on heparanase expression and invasion ability gastric cancer cells. METHODS: A heparanase mRNA-targeting double-stranded siRNA was designed with the bioinformatics technology. Human gastric cancer cells of the line SGC7901 were cultured and transfected with the siRNA of the concentrations of 5, 10, 20, and 40 nmol/L respectively. Forty-eight hours later RT-PCR and Western blotting were applied to detect the mRNA and protein expression of heparanase. Millicell chamber assay was performed to detect the invasion ability of the SGC7901 cells. Blank control group and negative control group were set. RESULTS: The mRNA expression level of the cells transfected with the siRNA of the concentrations 20 nmol/L and 40 nmol/L were 0.207 +/- 0.095 and 0.200 +/- 0.085 respectively, both significantly lower than that of the control group (0.60 +/- 0.09, both P < 0.05). Western blotting showed that the protein expression of heparanase of the different siRNA subgroups were all decreased dose-dependently; and no heparanase band was seen in the 40 nmol/L subgroup. The invasion rate of the siRNA group was significantly lower than that of the control group with a mean inhibition rate of (61 +/- 36)%. CONCLUSION: RNAi inhibits the expression of heparanase and the invasion ability of human gastric cancer cells. Heparanase may be a new target in treatment of gastric cancer's metastasis.
2 citations