L
Lin Lei Chen
Researcher at Li Ka Shing Faculty of Medicine, University of Hong Kong
Publications - 3
Citations - 2917
Lin Lei Chen is an academic researcher from Li Ka Shing Faculty of Medicine, University of Hong Kong. The author has contributed to research in topics: Viral load & Respiratory tract infections. The author has an hindex of 3, co-authored 3 publications receiving 2380 citations.
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Journal ArticleDOI
Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study.
Kelvin K. W. To,Owen Tak Yin Tsang,Wai Shing Leung,Anthony Raymond Tam,Tak Chiu Wu,David Christopher Lung,Cyril C. Y. Yip,Jian Piao Cai,Jacky Man Chun Chan,Thomas Shiu Hong Chik,Daphne Pui-Ling Lau,Chris Yau Chung Choi,Lin Lei Chen,Wan Mui Chan,Kwok-Hung Chan,Jonathan Daniel Ip,Anthony Chin-Ki Ng,Rosana W.S. Poon,Cui Ting Luo,Vincent C.C. Cheng,Jasper Fuk-Woo Chan,Jasper Fuk-Woo Chan,Ivan Hung,Zhiwei Chen,Honglin Chen,Kwok-Yung Yuen +25 more
TL;DR: The serial respiratory viral load of SARS-CoV-2 in posterior oropharyngeal saliva samples from patients with COVID-19, and serum antibody responses from patients infected with severe acute respiratory syndrome coronavirus 2 are ascertained.
Journal ArticleDOI
High neutralizing antibody titer in intensive care unit patients with COVID-19.
Li Liu,Kelvin K. W. To,Kelvin K. W. To,Kwok-Hung Chan,Yik Chun Wong,Runhong Zhou,Ka Yi Kwan,Carol Ho-Yan Fong,Lin Lei Chen,Charlotte Yee Ki Choi,Lu Lu,Owen Tak Yin Tsang,Wai Shing Leung,Wing Kin To,Ivan Hung,Kwok-Yung Yuen,Kwok-Yung Yuen,Zhiwei Chen +17 more
TL;DR: The data suggested that SARS-CoV-2 was unlikely to have silently spread before the COVID-19 emergence in Hong Kong, and ICU patients had an accelerated and augmented NAb response compared to non-ICU patients, which was associated with disease severity.
Journal ArticleDOI
Improved Detection of Antibodies against SARS-CoV-2 by Microsphere-Based Antibody Assay.
Carol Ho-Yan Fong,Jian Piao Cai,Thrimendra Kaushika Dissanayake,Lin Lei Chen,Charlotte Yee Ki Choi,Lok Hin Wong,Anthony Chin-Ki Ng,Polly K.P. Pang,Deborah Tip Yin Ho,Rosana W.S. Poon,Tom Wai-Hin Chung,Siddharth Sridhar,Kwok-Hung Chan,Jasper Fuk-Woo Chan,Ivan Hung,Kwok-Yung Yuen,Kelvin K. W. To +16 more
TL;DR: A novel microsphere-based antibody assay (MBA) for detecting immunoglobulin G (IgG) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleoprotein (NP) and spike protein receptor binding domain (RBD) is developed and evaluated.