L
Lin Ling Cheng
Researcher at University of Colorado Denver
Publications - 3
Citations - 267
Lin Ling Cheng is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Nonalcoholic fatty liver disease & Innate immune system. The author has an hindex of 3, co-authored 3 publications receiving 208 citations.
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Journal ArticleDOI
Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease.
Rachel H. McMahan,Xiaoxin X. Wang,Lin Ling Cheng,Tibor I. Krisko,Maxwell L. Smith,Karim C. El Kasmi,Mark Pruzanski,Luciano Adorini,Lucy Golden-Mason,Lucy Golden-Mason,Moshe Levi,Hugo R. Rosen,Hugo R. Rosen +12 more
TL;DR: Treatment of a murine model of nonalcoholic fatty liver disease with a dual FXR/TGR5 agonist decreased intrahepatic inflammation and altered the immune phenotype of monocytes and macrophages, indicating potential targeting strategies for treatment of NAFLD.
Journal ArticleDOI
Dietary Lipids Differentially Shape Nonalcoholic Steatohepatitis Progression and the Transcriptome of Kupffer Cells and Infiltrating Macrophages.
Brett McGettigan,Rachel H. McMahan,David J. Orlicky,Matthew A. Burchill,Thomas Danhorn,Prashanth Francis,Lin Ling Cheng,Lucy Golden-Mason,Claudia Jakubzick,Hugo R. Rosen +9 more
TL;DR: Findings indicate that fat and cholesterol synergize to alter macrophage phenotype, and they also challenge the dogma that KCs are purely proinflammatory in NASH.